摘要
目的:探讨不同剂量舒芬太尼全麻诱导对男性微创手术患者术后躁动的影响。方法:选取2013年1月—2016年1月湖北省公安县人民医院收治的择期行微创手术患者90例作为研究对象,以随机数字表法分为A、B、C组,每组30例。三组患者进行全麻诱导,给予咪达唑仑0.04 mg/kg、丙泊酚2 mg/kg、维库溴胺0.1 mg/kg;A、B、C组患者分别给予舒芬太尼0.2、0.4、0.6μg/kg。对比观察三组患者的麻醉、拔除气管导管、苏醒时间,以及视觉模拟评分、镇静-躁动评分、简易精神状态评估量表评分。结果:三组患者麻醉时间的差异无统计学意义(P>0.05);A组患者拔除气管导管及苏醒时间明显短于B、C组,差异均有统计学意义(P<0.05),B、C组的差异无统计学意义(P>0.05)。苏醒后1、10 min时,C组患者视觉模拟评分、镇静-躁动评分明显低于A、B组,差异均有统计学意义(P<0.05);三组患者简易精神状态评估量表评分的差异均无统计学意义(P>0.05)。结论:使用0.6μg/kg的舒芬太尼全麻诱导时可明显消除男性微创手术患者术后躁动。
OBJECTIVE： To probe into the effect of different dosages of sufentanil in general anesthesia induction on postoperative agitation of minimally invasive surgery for male patients. METHODS： 90 patients undergoing minimally invasive surgery admitted into Hubei Gong＇an County People＇s Hospital from Jan. 2013 to Jan. 2016 were selected and divided into group A,group B and group C via random number table,with 30 cases in each group. All three groups were conducted general anesthesia induction with 0. 04 mg/kg of midazolam,2 mg/kg of propofol and0. 1 mg/kg of vecuronium; group A,group B and group C were respectively given 0. 2,0. 4 and 0. 6 μg/kg of sufentanil. The anesthesia duration, endotracheal tubes removing time and awaking time of three groups were observed,differences of the visual analogy scores（ VAS）,sedation-agitation scores（ SAS） and mini-mental state examination（ MMSE） scores of three groups were compared. RESULTS： There was no statistical significance in the difference of anesthesia duration among three groups（ P〉0. 05）; the endotracheal tubes removing time and awaking time of group A were significantly shorter than those of group B and group C,with statistically significant difference（ P〈0. 05）,while no statistical significance was found between group B and group C（ P〉0. 05）. At 1 and 10 minutes after recovery,the VAS and SAS of group C were significantly lower than those of group A and group B,with statistically significant difference（ P〈0. 05）; and there were no statistical significance in differences of MMSE scores among three groups（ P〉0. 05）. CONCLUSIONS： Induced anesthesia of 0. 6 μg/kg of sufentanil can effectively eliminate postoperative agitation of minimally invasive surgery for male patients.
出处
《中国医院用药评价与分析》
2017年第9期1198-1200,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
舒芬太尼
全麻诱导
导尿管
术后躁动
Sufentanil
General anesthetic induction
Catheter
Postoperative agitation
