摘要
目的探讨慢性胆囊炎患者抑郁与胆囊幽门螺旋杆菌(HP)感染之间是否存在相关。方法选取在南京医科大学附属江宁医院普外科接受手术治疗的慢性胆囊炎患者作为研究对象,采用问卷及抑郁自评量表量表调查方法分析患者抑郁情况,并依据其严重程度进行分组,通过蜡块标本Warthy-Starry染色观察所有患者HP感染情况。χ~2检验及方差分析分析各组患者一般情况及HP感染情况是否存在差异。非参数相关分析患者的HP感染程度与患者的SDS量表评分是否相关。结果不同组患者HP感染情况存在显著差异(P=0.0002),患者的HP感染程度与患者的SDS量表评分存在显著相关(r=0.2696,P<0.0001)。结论慢性胆囊炎患者抑郁与胆囊HP感染显著相关。
Objective： To investigate the relationship between depression and helicobacter pylori infection in chronic cholecystitis patients. Methods： Patients undergoing cholecystectomy from the Department of General Surgery,Affiliated Jiangning Hospital of Nanjing Medical University were assessed with the self-rating depression scale（ SDS） for evaluation of their varied degree depression. The helicobacter pylori infection in paraffin specimens of all patients was detected by Warthy-Starry stain.The changes of helicobacter pylori infection and the difference of clinical factors in different groups were analyzed by Chi Square test and analysis of Variance. Spearman non parametric correlation analysis was used to observe the correlation between diverse level of helicobacter pylori infection and the SDS scale score. Results： Statistical analysis showed that the diverse level of helicobacter pylori infection was significantly correlated with the SDS scale score. Conclusion： A significantly positive correlation is found between different degree depression and the diverse level of helicobacter pylori infection in chronic cholecystitis patients.
作者
何泽民
张辉
HE Ze-min ZHANG Hui(Dept. of General Surgery, Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100 ,China)
出处
《泰山医学院学报》
CAS
2017年第9期1006-1007,共2页
Journal of Taishan Medical College
关键词
慢性胆囊炎
抑郁
幽门螺旋杆菌
胆囊收缩素
chronic cholecystitis
depression
helicobacter pylori
cholecystokinin
