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用吉非替尼对晚期非小细胞肺癌患者进行治疗的效果研究 被引量:2

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摘要 目的:探讨用吉非替尼对晚期非小细胞肺癌(NSCLC)患者进行治疗的临床效果。方法:选取江苏省泗洪县人民医院肿瘤科收治的100例IIIb期、IV期NSCLC患者作为研究对象。将其随机分为观察组和对照组。为观察组患者应用吉非替尼进行治疗,为对照组患者应用培美曲塞进行治疗。对比两组患者的临床疗效和治疗前后其TGF-α、CA21-1的水平。结果:1)观察组患者的疾病缓解率为38%,对照组患者的疾病缓解率为11%。与对照组患者相比,观察组患者的疾病缓解率更高,差异有统计学意义(P<0.05)。2)治疗前,两组患者TGF-α、CA21-1的水平相比,差异无统计学意义(P>0.05)。治疗后,两组患者TGF-α、CA21-1的水平均较治疗前明显下降,差异有统计学意义(P<0.05)。与对照组患者相比,观察组患者治疗后其TGF-α、CA21-1的水平均更低,差异有统计学意义(P<0.05)。结论:用吉非替尼对晚期NSCLC患者进行治疗的临床效果显著,可有效地提高其病情的缓解率,降低其TGF-α、CA21-1的水平。
作者 舒坚
出处 《当代医药论丛》 2017年第16期119-120,共2页
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