摘要
目的着重探讨非糖尿病急性冠脉综合征患者apoB/apoA1和BMI的水平变化及其与急性冠脉综合征发病风险的相关性。方法收集2014年3月至2016年6月于清远市人民医院心血管内科住院行冠脉造影术符合急性冠脉综合征诊断标准并无糖尿病的患者109例为研究对象,另外收集同期本院健康体检中心排除冠心病及糖尿病的健康体检者97例为对照。登记所有研究对象的临床资料性别、年龄、BMI、既往病史等临床资料,次日清晨空腹采集血样。结果与对照组比较,非糖尿病急性冠脉综合征患者BMI、血清apoB/apoA1显著增高。BMI、吸烟史、冠心病家族史、apoB/apoA1与非糖尿病急性冠脉综合征呈正相关(P<0.05)。结论BMI、apoB/apoA1可能是非糖尿病急性冠脉综合征发病风险的危险因素,减轻体重和调脂治疗是预防冠心病或减慢冠心病患者冠状动脉粥样硬化进展的重要措施。
Objective To discuss the association between apoB/apoA1 and BMI and the occurrence of non-diabetic acute coronary syndrome （ACS）.Methods 109 patients those who hospitalized in cardiovascular medicine department of Qingyuan PeopleJs Hospital of Guangzhou Medical University during March 2014 and June 2016 and diagnosed as ACS and without diabetic were recruited as non-diabetic ACS group, another 97 subjects from Health Department without coronary disease and diabetes in the same period as control group. Registered clinical data of all subjects： sex, age, BMI and anamnesis, collected venous blood. Results Compared with control group, the BMI, apoB/apoA1 level was significantly increased in non-diabetic ACS group. BMI, smoking, family history of coronary disease and apoB/apoA1 level was positively correlated with the risk of Non- diabetic ACS （P〈0.05）. Conclusions In non-diabetic ACS patients, both BMI and apoB/apoA1 might be the indicators of coronary disease. Losing weight and lipid- regulatory treatment are the important measures of preventing coronary heart disease.
作者
张舒媚
温伟谊
黎秀莲
罗红丽
刘婉菊
ZHANG Shu-mei(Cardiovascular medicine department, the sixth affiliated hospital of Guangzhou Medical University ＆ Qingyuan People＇s Hospital, Qingyuan , Guangdong , 511500, China)
出处
《齐齐哈尔医学院学报》
2017年第15期1749-1751,共3页
Journal of Qiqihar Medical University
