摘要
目的观察小儿变应性鼻炎伴变应性哮喘采取匹多莫德辅助治疗的临床效果。方法选取医院收治的小儿变应性鼻炎伴变应性哮喘患儿80例,按照用药方案不同分为常规组和干预组,每组40例。常规组给予常规治疗,干预组在常规治疗基础上加用匹多莫德治疗,观察2组患儿治疗前后鼻炎及哮喘症状积分状况,治疗前后免疫指标(IgM、IgG)及炎性反应指标(CRP、IL-8)水平,治疗前后肺功能[第1秒用力呼气容积(FEV_1)、最大呼气峰流速(PEF)]状况。结果干预组患儿治疗后症状评分、免疫指标、炎性反应指标、肺功能指标与常规组比较均明显较优,差异有统计学意义(P均<0.01)。结论小儿变应性鼻炎伴变应性哮喘患儿采取匹多莫德辅助治疗效果优良。
Objective Observation of the clinical effect of Pidotimod adjuvant therapy in children with allergic rhinitis and allergic asthma. Methods 80 children with allergic rhinitis and allergic asthma were divided into routine group and intervention group according to different treatment regimen with each group of 40 cases. Conventional group was given conventional treatment and intervention group used Pidotimod treatment on the basis of conventional treatment. The scores of rhinitis and asthma symptoms,immune indicators（ IgM、IgG）,and inflammatory response indicators（ CRP,IL-8） level,pulmonary function[FEV_1,maximal expiratory flow rate（ PEF） ]status and maximum expiratory peak flow rate（ PEF） condition,before and after treatment of the 2 groups were observed. Results Compared with the conventional group,the symptom score,immune index,inflammatory response index and pulmonary function index of the intervention group were significantly better than those of the conventional group（ P〈0. 01）. Conclusion Children with allergic rhinitis accompany allergic asthma adopted by Pidotimod adjuvant treatment has excellent clinical efficacy. The effect of German adjuvant therapy is excellent.
出处
《临床合理用药杂志》
2017年第26期15-16,22,共3页
Chinese Journal of Clinical Rational Drug Use
