摘要
目的考察小包装中药饮片地黄中梓醇和毛蕊花糖苷的质量稳定性。方法用2015年版《中国药典》梓醇和毛蕊花糖苷的检测方法,先进行影响因素(高温、高湿、强光照射)实验的考察,再采用加速实验和长期实验考察其质量稳定性。结果小包装中药饮片地黄在高温条件下梓醇含量明显降低,真空包装小包装饮片地黄质量稳定性好于常规包装。在25℃、RH 60%条件下储存的小包装中药饮片地黄梓醇和毛蕊花糖苷稳定性超过6个月。结论该研究可为小包装中药饮片地黄的保存条件和有效期提供依据。
Objective To investigate the quality stability of catalpol and verbascoside in small package of Chinese medicine pieces of Rehmannia glutinosa. Methods According to the content detection method in Chinese Pharmacopoeia （2005 edition）, the different factors （high temperature, high humidity and strong light） were analyzed firstly, and then the accelerated experiment and long-term experiment were used to investigate its quality and stability. Results The content of catalpol was significantly decreased under high temperature. The quality and stability of small package pieces of Rehmannia glutinosa in vacuum packaging was better than that in conventional packaging. Under the conditions of 25 ℃ and RH 60%, the small package of Chinese medicine pieces of Rehmannia glutinosa was valid for 6 months. Conclusion The study can provide the basis for the preservation condition and validity period of small package of Chinese medicine pieces of Rehmannia glutinosa.
作者
汪露露
许纪锋
钱勇
谢绚影
梅利中
金金花
WANG Lu-Lu XU Ji-Feng QIAN Yong XIE Xuan-Ying MEI Li-Zhong JIN Jin-Hua(Shanghai Naturestandard R＆D Biotech Co.,Ltd., Shanghai 201203, China Shanghai Huapu Chinese Herbal Medicine Co., Ltd., Shanghai 201203, China)
出处
《食品安全质量检测学报》
CAS
2017年第8期3202-3206,共5页
Journal of Food Safety and Quality
基金
上海市科委科研计划项目(15DZ229190)~~
关键词
小包装中药饮片
地黄
梓醇
毛蕊花糖苷
质量稳定性
影响因素实验
small package of Chinese medicine pieces
Rehmannia glutinosa
catalpol
verbascoside
quality stability
influencing factors experiment
