摘要
目的探究在妇科恶性肿瘤患者中,宫颈癌和卵巢癌与梅毒螺旋体感染的相关性。方法选取2013年2月-2016年8月医院妇科住院治疗的宫颈癌患者269例和卵巢癌患者106例为研究对象,并选取1 000例普通患者作为对照,对宫颈癌组、卵巢癌组和普通患者组进行梅毒螺旋体感染检查,比较三组患者梅毒螺旋体感染率,对宫颈癌和卵巢癌患者按照术后病理学诊断进行分型,比较各主要类型患者的梅毒螺旋体感染率;比较宫颈癌组患者不同分期、不同年龄段、不同学历区间的梅毒螺旋体感染率。结果宫颈癌组患者感染梅毒螺旋体31例,感染率为11.5%,卵巢癌组患者感染梅毒螺旋体4例,感染率为3.8%,普通患者组感染梅毒螺旋体34例,感染率为3.4%,宫颈癌组与普通患者组梅毒螺旋体感染率比较差异有统计学意义(P<0.05),而卵巢癌组与普通患者组梅毒螺旋体感染率比较差异无统计学意义;宫颈鳞状细胞癌患者感染率为12.6%,宫颈腺癌患者感染率为3.2%,腺鳞癌患者感染率为0,宫颈鳞状细胞癌患者梅毒螺旋体感染率与其他宫颈癌病理分型比较,差异有统计学意义(P<0.05),浆液性囊腺癌患者感染率为4.1%,黏液性囊腺癌患者感染率为2.8%,子宫内膜样癌患者感染率为4.8%,卵巢癌3种病理分型患者梅毒螺旋体感染率比较差异无统计学意义;宫颈癌Ⅰ期患者感染率为16.2%,宫颈癌Ⅱ期患者感染率为6.3%,宫颈癌组不同分期感染率比较,差异有统计学意义(P<0.05);30~39岁区间梅毒螺旋体感染率为18.5%,40~49岁区间感染率为24.6%,50~59岁区间感染率为5.6%,>60岁区间感染率为2.0%,宫颈癌组不同年龄区间的感染率比较,差异有统计学意义(P<0.05);高中学历以下患者感染率为16.2%,高中学历及以上患者感染率为5.8%,宫颈癌组不同学历区间的感染率比较,差异有统计学意义(P<0.05)。结论宫颈癌患者有更大可能性感染梅毒螺旋体,卵巢癌患�
OBJECTIVE To investigate the correlation of cervical cancer and ovarian cancer in patients with Treponema pallidum infections.METHODS A total of 269 patients with cervical cancer and 106 patients with ovarian cancer diagnosed and treated in our department from Feb.2013 to Aug.2016 were selected,and 1000 cases of common patients were selected as control.T.pallidum infection was examined in cervical cancer group,ovarian cancer group and control group,and the infection rates of T.pallidum of the three groups were compared.Patients with cervical cancer and ovarian cancer were classified according to pathological diagnosis after operation,and the rates of T.pallidum infections in each major group were compared.The infection rates of T.pallidum in different stages,ages and educational levels of cervical cancer group were compared.RESULTS There were 31 cases of T.pallidum infections in patients with cervical cancer,with the infection rate of 11.5%,4 cases in ovarian cancer group,with the infection rate of 3.8%,and 34 cases in general patients,with the infection rate of 3.4%.There was significant difference in the T.pallidum infection rate between cervical cancer group and control group（P〈0.05）,and there was no significant difference in the T.pallidum infection rate between ovarian cancer group and control group.The infection rate of cervical squamous cell carcinoma patients was 12.6%,of cervical adenocarcinoma patients was 3.2%,and of adenosquamous squamous patients was 0.There were significant differences of T.pallidum infection rate between cervical squamous cell carcinoma patients and patients with other pathological types of cervical cancers（P〈0.05）.The infection rate of serous cystadenocarcinoma patients was 4.1%,of mucinous cystadenocarcinoma patients was 3.6%,and of endometrial carcinoma patients was 4.7%,and the differences of T.pallidum infection rate in patients with the three different pathological types of ovarian carcinoma were not significance.The infection rate of stage I cervical cancer patie
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第17期3997-3999,4003,共4页
Chinese Journal of Nosocomiology
关键词
宫颈癌
卵巢癌
梅毒螺旋体
感染
Cervical cancer
Ovarian cancer
Treponema pallidum
Infection
