摘要
目的调查分析海南地区百岁老人网织红细胞各项参数特点。方法选取百岁老人68例,18~83岁健康人群129例,采用Sysmex XT-4000i型全自动血液细胞分析仪分析网织红细胞五项参数:网织红细胞绝对值(RET#)、网织红细胞百分率(RET%)、高荧光网织红细胞百分率(HFR%)、中荧光网织红细胞百分率(MFR%)、低荧光网织红细胞百分率(LFR%)。结果百岁老人HGB[(113.38±15.09)g/L]、RET%[(1.04±0.37)]、RET#[(41.37±15.04)×109/L]、MCH[(28.43±2.59)pg]、MCHC[(316.00±9.5)g/L]和RBC[(4.00±0.50)×1012/L]均低于健康成年人,差异均有统计学意义(P<0.05);HFR%(0.34±0.43)、MFR%(3.43±2.50)、LFR%(96.23±2.67)和MCV(89.94±7.01)同健康成年人比较差异均无统计学意义(P>0.05);百岁老人HGB仅与RET#存在弱相关性(r=0.298,P<0.05),而与RET%、RET#、HFR%、MFR%和MFR%均无相关性(P>0.05)。结论百岁老人骨髓造血能力衰退,HGB和网织红各项参数均低于成年人群,需独立制定相应参考范围才能与百岁老人疾病诊断匹配。
Objective To investigate and analyze the Hainan centenarians＇ reticulocyte parameters characteristics. Methods Sixty-eight centenarians and 129 healthy adults aged from 18 to 83 was selected, and five reticulocyte parameters were analyzed by Sysmex XT-4000 i automatic blood cell analyzer, including reticulocyte percentage（RET%）, reticulocyte absolute value（RET#）, high fluorescent reticulocyte percentage（HFR%）, middle fluorescent reticulocyte percentage（MFR%）, and low fluorescent reticulocyte percentage（LFR%）. Results The HGB, RET%, RET#,MCH, MCHC and RBC in Hainan centenarians were respectively（113.38±15.09） g/L,（1.04±0.37）,（41.37±15.04）×10^9/L,（28.43±2.59） pg,（316.00±9.5） g/L and（4.00±0.50）×10^12/L, significantly lower than those in the healthy adults（P〈0.05）;The HFR%, MFR%, LFR%, and MCV in Hainan centenarians were（0.34±0.43）,（3.43±2.50）,（96.23±2.67） and（89.94±7.01）, which showed no statistically significant differences with those of the healthy adults（P〉0.05）; HGB only had weak correlation with RET# in the centenarians（r=0.298,P〈0.05）, but it showed no correlation with RET%, RET#,HFR% and MFR%（P〉0.05）. Conclusion Centenarians have hypofunction in bone marrow hematopoiesis, and their HGB and reticulocytes are lower than those of adults. It is necessary to formulate the appropriate reference independently to match the disease diagnosis of centenarians.
作者
陈龙琴
于帅
肖征
CHEN Long-qing YU Shuai XIAO Zheng(Department of Clinical Laboratory, Hainan Branch of Chinese PLA General Hospital, Sanya 5720]3, Hainan, CHIN)
出处
《海南医学》
CAS
2017年第16期2642-2644,共3页
Hainan Medical Journal
基金
海南省重点研发项目(编号:ZSYF2016135)
关键词
百岁老人
网织红细胞
海南
Centenarians
Reticulocyte（RET）
Hainan
