摘要
近年来,免疫肿瘤治疗发展迅速,已经成为继手术、放疗、化疗、靶向治疗后癌症的另一有效治疗手段。目前已有多个免疫检查点相关药物获批用于多种恶性肿瘤的治疗,而且越来越多的潜在治疗靶点受到关注。本综述旨在根据肿瘤-免疫循环中的不同环节,对不同机制的免疫肿瘤治疗药物研究现状和临床前景进行概述和展望。
Recently, immune-oncologic therapy advanced rapidly and has been defined as another option, following surgery, radiotherapy, chemotherapy and molecular targeted therapy, for treatment of malignant diseases. To date, several immune checkpoint inhibitors and compounds have been approved to treat various of malignant diseases with efficiency. Meanwhile, more and more potential therapeutic targets in processes of the cancer immunity have been noticed. We aimed to summarize the research status and clinical prospects of novel immune-oncologic treatment agencies targeted to different steps of the cancer-immunity cycle.
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2017年第9期645-651,共7页
Chinese Journal of Lung Cancer
关键词
肿瘤
免疫肿瘤治疗
免疫检查点抑制剂
Neoplasms
Immuno-oncology therapy
Immune checkpoint inhibitor
