摘要
目的探讨红细胞分布宽度(RDW)对急性胰腺炎(AP)严重程度的评估价值。方法回顾性研究收集2013年5月~2016年5月南方医科大学南方医院消化内科住院的急性胰腺炎患者527例,按疾病严重程度分为轻度(MAP)组、中度(MSAP)组、重度(SAP)组,纳入同期非急性胰腺炎患者105例作为对照组,收集患者的一般资料及RDW,以经典评估指标"血糖"和"血钙"为对比进行统计与分析。结果急性胰腺炎组与对照组之间RDW、血糖(Glu)、血钙(Ca)差异有统计学意义(P<0.05);SAP患者的RDW、Glu明显高于MAP及MSAP患者,Ca则明显低于MAP及MSAP患者(P<0.05);RDW(P<0.05,OR=3.374)、Glu(P<0.05,OR=2.343)、Ca(P<0.05,OR=2.182)均为急性胰腺炎的独立危险因素;ROC曲线预测SAP曲线下面积为RDW(0.801)>Glu(0.658)>Ca(0.227)。结论 RDW是评估急性胰腺炎严重程度的有效指标。
Objective To explore the value of red blood cell distribution width （RDW） in assessment of the severity of acute pancreatitis （AP）. Methods This retrospective analysis was conducted among 527 patients with AP treated in our department from May, 2013 to May, 2016. According to the severity of the condition, the patients were classified into mild acute pancreatitis （MAP） group, moderately severe acute pancreatitis （MSAP） group and severe acute pancreatitis （SAP） group, with 105 subjects without AP as the control group. The demographic data and data of RDW were collected from all cases to evaluate the value of RDW in assessing the severity of AP in comparison with classic evaluation indicators glucose （Glu） and calcium （Ca）. Results The patients with AP and the control subjects showed significant differences in RDW, Glu and Ca （P〈0.05）. RDW and Glu was significantly higher but Ca was significantly lower in SAP patients than in MAP and MSAP patients （P〈0.05）. Binary classification logistic regression analysis showed that Glu （P〈0.05, OR=2.343）, Ca （P〈0.05, OR=2.182） and RDW （P〈0.05, OR=3.374） were all independent risk factors for AP. The area under the ROC curve for predicting SAP decreased in the order of RDW （0.801）, Glu （0.658）, and Ca （0.227）. Conclusion RDW is a useful indicator for evaluation of the severity of AP.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2017年第7期993-996,共4页
Journal of Southern Medical University
基金
广州市科技计划项目(2014Y2-00088)
国家消化系统疾病临床医学研究中心科技支撑项目(2015BAI13B07)
关键词
红细胞分布宽度
急性胰腺炎
严重程度
red blood cell distribution width
acute pancreatitis
severity
