摘要
目的探讨胚胎发育不良性神经上皮瘤(DNT)的MRI影像表现与临床病理特点,提高对胚胎发育不良性神经上皮瘤的认识。方法回顾性分析8例手术病理证实的胚胎发育不良性神经上皮瘤患者的MRI表现与临床病理特点。结果 8例患者中,男3例,女5例,均有癫痫病史;病灶累及大脑半球皮层及皮层下,其中颞叶5例、额叶2例、颞顶叶1例;MRI表现为长T_1、稍长T_2信号,其中1例T1WI高低混杂信号;4例病灶呈类三角形,3例病灶内多发小囊变,1例病灶呈类圆形。7例病灶周无水肿。增强后6例病灶无强化,2例病灶轻度强化。病理学显示肿瘤主要由少突胶质细胞样细胞、神经元和星形细胞组成。临床上该病好发于儿童或年轻人。结论 DNT属于良性肿瘤,其MRI表现具有一定特征,结合临床及影像表现,应考虑到本病的可能性。
Objective To analyze the MRI and pathological findings of dysembryoplastic neuroepithelial tumor（ DNT） for better understanding of DNT. Methods The MR and pathological findings of DNT in 8 cases were analyzed retrospectively. Results Of 8 patients,3 were males and5 females. All had epilepsia as the main symptom. The lesions of all 8 patients were located in the cerebral cortex or mostly in the cerebral cortex. The origin of the primary tumors was in temoral lobe in 5,2 in frontal lobe and 1 in temporal and parietal lobe. The lesions appeared as long T_1 and T_2 signal intensity,in addition,the MRI signal of 1 case was mixed. 4 lesions were triangular. The lesions of 3 cases showed multiple cystic formation,1 looked similar to round. 7 were devoid of peritumoral edema or mass effect. After Gd-DTPA injection,6 cases had no enhancement and 2 were slightly enhanced. Pathology showed the tumor was composed of oligodendrocyte,mature astrocytes and neurons. This disease occurred in children or adolescents clinically. Conclusions DNT is a benign tumor with characteristic MRI imaging findings. If clinical coincident with MRI findings,DNT should be considered.
出处
《临床神经外科杂志》
CAS
2017年第4期267-270,共4页
Journal of Clinical Neurosurgery
基金
南京市卫生青年人才培养项目第二层次基金资助项目(QRX11115)
关键词
胚胎发育不良性神经上皮瘤
磁共振成像
病理
dysembryoplastic neuropithelial tumors
magnetic resonance imaging
pathology
