摘要
目的观察地尔硫与地高辛联合应用在治疗风湿性心脏病并快速型心房颤动的临床效果。方法选取2016年1月15日~2017年3月12日我院住院部收治的风湿性心脏病并快速型心房颤动患者40例。将其按照随机抽取的方式分为两组,观察组20例给予地尔硫联合地高辛治疗,对照组20例给予地高辛治疗。观察两组患者的临床总有效率、生活质量、不良反应发生率、心功能改善情况。结果观察组患者的临床总有效率为95.00%,高于对照组的60.00%(P<0.05);观察组患者的生理功能[(91.44±6.33)分]、社会功能[(90.26±6.25)分]、心理功能[(88.43±5.45)分]、物质生活[(90.35±6.30分)]评分均高于对照组[(72.45±4.25)、(70.15±4.20)、(71.21±4.22)、(75.34±4.30)分](P<0.05);观察组患者的不良反应发生率为5.00%,低于对照组的35.00%(P<0.05);观察组患者心功能改善Ⅰ期8例,心功能改善Ⅱ级12例,明显优于对照组(Ⅰ级5例,Ⅱ级15例)(P<0.05)。结论地尔硫与地高辛联合治疗风湿性心脏病并快速型心房颤动患者具有显著的临床效果,不仅可以确保治疗效果,并且还能降低不良反应发生率,具有临床推广的价值。
Objective To observe the clinical effect of Diltiazem combined with Digoxin in the treatment of rheumatic heart disease with rapid atrial fibrillation.Methods Forty patients with rheumatic heart disease and rapid atrial fibrillation admitted into our hospital from January 15 th,2016 to March 12 th,2017 were selected in this study.They were evenly divided into two groups in random,observation group was treated by Diltiazem combined with Digoxin,and control group was only treated by Digoxin.The total clinical effective rate,quality of life,incidence of adverse reactions,and improvement of cardiac function were observed in the two groups.Results The total clinical effective rate was 95.00% in the observation group,much higher than that in the control group accounting for 60.00%（P〈0.05）.In the observation group,the scores of quality of life including physiological function,social function,psychological function,and material life were（91.44±6.33）,（90.26±6.25）,（88.43±5.45） points,and（90.35±6.30） points respectively,was higher than that in the control group [（72.45±4.25）,（70.15±4.20）,（71.21±4.22）,（75.34±4.30） points]（P〈0.05）.The incidence of adverse reactions in the observation group was 5.00%,lower than that in the control group accounting for 35.00%（P〈0.05）.The improvement of cardiac function in the observation group was 8 cases in grade Ⅰ and 12 cases in grade Ⅱ,which was superior to those in the control group,5 cases in grade Ⅰ and 15 cases in grade Ⅱ（P〈0.05）.Conclusion Diltiazem combined with Digoxin in the treatment of rheumatic heart disease complicated with rapid atrial fibrillation obtains a remarkable clinical effect,not only ensures the therapeutic effect,but also reduces the incidence of adverse reactions,which has a value for clinical promotion.
出处
《中国当代医药》
2017年第24期66-68,共3页
China Modern Medicine
关键词
地尔硫
地高辛
风湿性心脏病
快速型心房颤动
临床效果
Diltiazem
Digoxin
Rheumatic heart disease
Rapid atrial fibrillation
Clinical effect
