摘要
目的应用Titan对初筛未通过的听力高危新生儿进行复筛,评价Titan在新生儿听力筛查及听力诊断中的作用。方法对223例(446耳)初筛未通过的听力高危新生儿在出生后第40天左右(前后不超过3 d)应用Titan分别行自动听性脑干反应(automated auditory brainstem response,AABR)、耳声发射(otoacoustic emission,OAE)、声导抗检测;AABR、OAE系统自动判断是否通过,声导抗检测采用1 KHz探测音,鼓室压低于-50 dapa、声顺<0.3 ml认定为异常;统计数据,并分析其结果。结果 AABR复筛通过436耳,复筛通过率为97.76%(436/446),OAE复筛通过348耳,通过率为78.03%(348/446),二者差异有显著性(χ~2=81.59,P<0.05);声导抗检测异常者共81耳,异常率为18.16%(81/446),其中在AABR复筛未通过10耳中存在声导抗检测异常者共1耳,异常率为10%(1/10),OAE复筛未通过98耳中存在声导抗检测异常者共57耳,异常率为58.16%(57/98),二者差异有显著性(χ~2=6.64,P<0.05)。结论 Titan是一款集AABR、OAE、声导抗检测于一体的新型听力检测仪器,应用于新生儿听力筛查可有效降低假阳性率,并能及早评价患儿的中耳功能,鼓室负压、咽鼓管功能不良是新生儿听力筛查假阳性率高的一个重要因素。
Objective To evaluate the role of Titan platform in newborn hearing screening and diagnosis by using it to re-screen heating in the high-risk newborns who failed in the initial screening. Methods 223 newborns （446 ears） aged about 40 days （not more than 3 days before and after） who failed to pass the initial hearing screening were enrolled in this study. Automated auditory brainstem response （AABR）, otoacoustic emission （OAE） and acoustic immittance measurement （AIM） were performed via Titan platform to all the 223 newborns. The AARB and OAE system can evaluate the results automatically. Abnormal AIM result was defined as tympanic pressure lower than -50 dapa or acoustic compliance less than 0.3 ml with 1KHz probe tone. All data were collected, the passing rates were obtained or calculated, and the results were statistically analyzed. Results 436 ears passed the secondary screening by AABR and 348 ears by OAE. The passing rates were 97.76% （436/446） and 78.03% （348/446） respectively. The difference was statistically significant （P 〈 0.05 ）. Furthermore, abnormal AIM result was detected in 81 ears with an abnormal rate of 18.16% （81/ 446）. Of the l0 ears failed secondary AABR heating screening, abnormal AIM result was detected in one with an abnormal rate of 10% （1/10）. Of the 98 ears failed secondary OAE hearing screening, abnormal AIM result was detected in 57 with an abnormal rate of 58.16% （ 57/98 ）. The difference was also statistically significant （ P 〈 0.05 ）. Conclusions Titan platform is a new hearing testing instrument with AABR, OAE and AIM. It can reduce the false positive rate effectively in newborn hearing screening and early evaluate the children＇ s middle ear function. Furthermore, negative middle ear pressure and Eustachian tube dysfunction are the important factors for high false positive rate in newborn hearing screening.
出处
《中国耳鼻咽喉颅底外科杂志》
CAS
2017年第4期350-352,共3页
Chinese Journal of Otorhinolaryngology-skull Base Surgery
基金
广东省医学科研基金立项课题(A2014317)
关键词
TITAN
新生儿
听力筛查
自动听性脑干反应
耳声发射
Titan
Newborn
Hearing screening
Automated auditory brainstem response
Otoacoustic emisson
