摘要
通过抗菌活性试验筛选了具有窄谱特性的抗菌肽,并分析了其溶血性.结果表明:抗菌肽C仅对大肠杆菌和金黄色葡萄球菌具有抗菌活性,而对其他6种革兰阴性菌、2种革兰阳性菌和3种真菌没有抗菌活性,对兔红细胞有较低的溶血性.结果为临床用药提供了帮助.
To screen the antimicrobial peptide with narrow spectrum,the antimicrobial peptides were screened with narrow spectrum characteristics through the antibacterial activity test,and its hemolytisis was analyzed.The results showed that the antibacterial peptide C had antibacterial activity only on Escherichia coli and Staphylococcus aureus, but had no antibacterial activity on the other six kinds of Gram-negative bacteria,two kinds of Gram-positive bacteria and three kinds of fungi,and had lower hemolytic on rabbit red blood cells.The result provides help for chnical medication.
出处
《河南科技学院学报（自然科学版）》
2017年第4期37-40,共4页
Journal of Henan Institute of Science and Technology(Natural Science Edition)
基金
国家自然科学基金(31672559)
河南省高校科技创新团队支持计划(15IRTSTHN)
河南科技学院高层次人才启动项目(2014020)
河南科技学院"百农英才"创新项目(BNYC2015-2-07
BNYC2015-2-09)
关键词
窄谱抗菌肽
筛选
溶血性
抗菌活性
narrow spectrum antibacterial peptide
screening
hemolysis
antibacterial activity
