摘要
目的研究替硝唑与硫酸庆大霉素行腹腔灌注治疗急性盆腔炎的临床效果。方法选择2012年2月至2016年6月在我院进行诊治的急性盆腔炎患者100例,随机分为观察组与对照组,每组50例。对照组患者采用静脉滴注替硝唑、头孢唑啉钠进行治疗,观察组患者采用腹腔灌注替硝唑、硫酸庆大霉素进行治疗,比较两组的临床治疗效果,记录两组患者的腹痛消失的时间、细菌培养阴性时间、住院时间及体温恢复正常时间,并通过电话或门诊对所有患者进行3个月的随访,记录并比较两组患者的复发情况。结果观察组的治疗总有效率为94.00%(47/50),明显高于对照组的76.00%(38/50)(P<0.05);观察组患者的腹痛消失时间、细菌培养阴性时间、住院时间、体温恢复正常时间及复发率均明显优于对照组(P<0.05)。结论替硝唑与硫酸庆大霉素行腹腔灌注治疗急性盆腔炎具有较好的临床效果,值得临床应用推广。
Objective To explore the clinical efficacy of tinidazole combined with gentamycin sulfate intraperitoneal chemoperfusion in the treatment of acute pelvic inflammatory disease. Methods A total of 100 cases of patients with acute pelvic inflammatory disease admitted in our hospital from February 2012 to June 2016 were enrolled in this study, and ran- domly divided into observation group and control group, with 50 cases in each group. Patients in the observation group per- formed tinidazole and gentamycin sulfate intraperitoneal chemoperfusion, while patients in the control group were given tinidazole and cephazolin sodium intravenous infusion, the clinical efficacy of the two groups were observed, and the time of abdominal pain disappearance, bacterial culture becoming negative, body temperature recovery and hospital stay of the two groups were compared, as well as the recurrence rate of the two groups after 3 months＂ follow-up by calling or outpa- tient service. Results The total effective rate of the observation group was 94.00% （47/50）, which was higher than 76.00% （38/50） of the control group, the difference was statistically significant （P〈0.05）. The time of abdominal pain disappearance, bacterial culture becoming negative, body temperature recovery, and hospital stay and recurrence rate in the observation group were better than those in the control group, the differences were significant （P〈0.05）. Conclusion Application of tinidazole and gentamycin sulfate intraperitoneal chemoperfusion in the treatment of acute pelvic inflammatory disease achieves better clinical efficacy, which is worthy of clinical promotion.
出处
《临床医学研究与实践》
2017年第25期87-88,共2页
Clinical Research and Practice
关键词
替硝唑
硫酸庆大霉素
腹腔灌注
急性盆腔炎
tinidazole
gentamycin sulfate
intraperitoneal chemoperfusion
acute pelvic inflammatory disease
