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壳聚糖宫颈抗菌膜在宫颈手术中的应用 被引量:5

Application of chitosan cervical antibacterial membrane in cervical surgery
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摘要 目的分析宫颈手术后给予壳聚糖宫颈抗菌膜的意义。方法 50例行宫颈环切或锥切术宫颈上皮内瘤变(CIN)Ⅱ~Ⅲ患者,采用双盲法分为对照组和观察组,各25例。对照组患者术后自然恢复,观察组患者术后给予壳聚糖宫颈抗菌膜治疗。比较两组术后阴道流血量、术后阴道流血时间、阴道流液时间、创面愈合时间、术后阴道细菌性阴道病(BV)及白带常规检查结果。结果两组患者术后阴道流血量比较差异具有统计学意义(P<0.05)。观察组术后阴道流血时间、阴道流液时间及创面愈合时间均明显短于对照组,差异具有统计学意义(P<0.05)。观察组术后阴道BV及白带常规检查检查正常率为80.00%,高于对照组48.00%,差异具有统计学意义(χ2=5.56,P<0.05)。结论宫颈手术后给予壳聚糖宫颈抗菌膜能减少术后阴道流血、流液,有止血和促进创面愈合之效,能预防感染,值得推广。 Objective To analyze the significance of chitosan cervical antibacterial membrane applied after cervical surgery. Methods A total of 50 cervical intraepithelial neoplasia (CIN) Ⅱ-Ⅲ patients undergoing leep or conization were divided by double - blind method into control group and observation group, with 25 cases in each group. The control group patients recovered after operation, and the observation group was treated with chitosan cervical antibacterial membrane for treatment. Comparison were made on postoperative vaginal bleeding volume, postoperative vaginal bleeding time, vaginal fluid time, wound healing time, postoperative vaginal bacterial vaginosis (BV) and leucorrhea routine examination results in two groups. Results Both groups had no statistically significant difference in postoperative vaginal bleeding volume (P〈0.05). The observation group had obviously shorter vaginal bleeding time, vaginal fluid time and wound healing time after operation than the control group, and their difference had statistical significance (P〈O.05). The observation group had higher postoperative vaginal BV and leueorrhea routine examination normal rate as 80.00% than 48.00% in the control group, and the difference had statistical significance (χ^2=5.56, P〈0.05). Conclusion Application of ehitosan cervical antibacterial membrane after cervical surgery can reduce postoperative vaginal bleeding, fluid, and it has the effect of hemostatie and promoting wound healing, along with preventing infection. So it is worth promoting.
作者 刘清青
出处 《中国实用医药》 2017年第21期29-31,共3页 China Practical Medicine
关键词 壳聚糖宫颈抗菌膜 子宫颈上皮内瘤变Ⅱ-Ⅲ 宫颈手术 LEEP刀 Chitosan cervical antibacterial membrane Cervical intraepithelial neoplasia Ⅱ-Ⅲ Cervicalsurgery Leep knife
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