摘要
目的探究老年轻度认知功能障碍(MCI)患者心血管危险因素的聚集情况。方法运用总体衰退量表(GDS)和简易精神状态量表(MMSE)进行认知状况横断面调查,根据MCI诊断标准将110名受试者分为MCI组(n=45)和健康对照组(n=65),比较两组之间心血管危险因素的聚集性。结果 (1)与健康对照组相比,MCI组的SBP,DBP,TG,TC,HDL-C均明显增高,而BMI则显著降低,差异具有统计学意义(P<0.05)。(2)MCI组患者合并高血压、糖尿病、血脂异常等各项心血管危险因素的比例及合并≥2RFs的比例均明显高于对照组,两组间比较差异均有统计学意义(P<0.05)。结论 MCI患者出现心血管危险因素聚集现象,应对此做出有效的干预措施,以减缓或阻止MCI的发生与发展。
Objectives To investigate the aggregation of cardiovascular risk factors and their clustering in elderly patients with mild cognitive impairment （MCI）. Methods A total of 110 subjects were divided into MCI group （ n = 45 ） and healthy control group （ n = 65）, according to the MCI diagnostic criteria by using the general recession scale （GDS） and the simple mental state scale （MMSE） ,and compared the clustering of cardiovascular risk factors between the two groups. Results ①Compared with the healthy control group, SBP, DBP, TG, TC, HDL-C were significantly increased in MCI group, while BMI was significantly decreased. The difference was statistically significant （ P 〈 0.05）. ②The ratio of cardiovascular risk factors such as hypertension, diabetes mellitus, dyslipidemia and ≥ cardiovascular risk factor（2RFs） in MCI group was significantly higher than that in control group （P 〈 0. 05）, and the difference between the two groups was statistically significant （ P 〈 0. 05 ）. Conclusion MCI patients with cardiovascular risk factors aggregation phenomenon, should make effective intervention measures to slow or prevent the occurrence and development of MCI.
出处
《中国老年保健医学》
2017年第4期37-39,共3页
Chinese Journal of Geriatric Care
基金
扬州市立项项目(项目名称:老年人轻度认知功能障碍患者环境和基因交互作用风险评估模型构建及干预性研究
项目编号:YZ2015054)
关键词
轻度认知功能障碍
危险因素
聚集性
mild cognitive dysfunction, risk factors, aggregation
