摘要
目的分析PET/CT在鼻咽癌的分期、再分期、临床分期中的应用及在监测疗效中的价值。方法选取2014年6月至2016年1月间我院收治的172例NPC患者作为本研究对象,使用GE Discovery DST PET/CT18F-FDG显像仪对患者行影像学检查;分析影像学检查在NPC的分期、再分期、临床分期中的应用,并探讨其在临床疗效检测时的应用价值。结果首次分期采用PET/CT影像学检查的诊断灵敏度及准确性均显著高于CT/MRI检测(P<0.05);再分期两组检测方法的诊断灵敏度、准确性、阳性预测值、阴性预测值差异具有统计学意义(P<0.05);临床疗效监测时两种检查方法的诊断灵敏度、准确性、阴性预测值差异具有统计学意义(P<0.05)。结论 PET/CT在NPC的分期、再分期、临床分期中的应用具有准确性、灵敏度较高的优点,且其在疗效监测时具有较好的临床应用价值。
Objective Analyze the application of PET/CT in staging, re-staging and clinical staging in nasopharyngeal carcinoma.Methods 172 cases of NPC patients were selected from June 2014 to January 2016 in our hospital as the object of study These patients underwent imaging examination, with the use of GE Discovery DST PET/CT 18F-FDG imaging;Then we performed statistical analysis of imaging in NPC staging, re-staging, clinical staging, and explored its application in detection of clinical curative effect.Results The first stage, then re-staging, clinical staging and curative effect monitoring results show that the PET/CT scan is better than that of CT/MRI;In the first stage, the diagnostic sensitivity and accuracy of examination by PET/CT effects were significantly higher than that of CT/MRI detection （P〈0.05）;in restaging, the sensitivity, accuracy, positive predictive effect of the examination by PET /CT value and negative predictive value were significantly higher than that of CT/MRI detection （P〈0.05）;In the stage of diagnosis, the diagnostic specificity, sensitivity and accuracy of examination by PET/CT effects were significantly higher than that of CT/MRI detection （P〈0.05）, In the clinical monitoring, the diagnostic sensitivity, accuracy and negative effect of the examination by PET/CT predictive value was significantly higher than that of CT/MRI （P〈0.05）.Conclusion The application of PET/CT in the staging, re-staging and clinical staging of NPC has the advantages of high accuracy and sensitivity, and it has good clinical application value in the detection of curative effect.
出处
《标记免疫分析与临床》
CAS
2017年第8期884-887,共4页
Labeled Immunoassays and Clinical Medicine
关键词
鼻咽癌
分期
再分期
临床分期
疗效监测
PET/CT
PET/CT
Nasopharyngeal carcinoma
Staging
Clinical stage
Therapeutic effect monitoring
