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西宁地区甲状腺结节相关因素的临床研究

The Clinical Study on Related Factors of Thyroid Nodules in Xining Area
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摘要 目的:了解西宁地区查体人群甲状腺结节的检出情况,分析结节的数目及性质、与甲状腺功能的关系以及可能的独立危险因素。方法:采用回顾性调查分析的研究方法对我院门诊查体人群的甲状腺超声结果进行了总结分析,分性别、年龄对甲状腺结节的检出率、数目及性质进行比较;同时比较正常组和有结节组甲状腺功能的变化;并采用多因素Logistic回归分析的方法,探讨甲状腺结节发生的独立危险因素。结果:(1)本研究显示西宁地区查体人群甲状腺结节检出率为38.5%,女性略高于男性(P<0.01);(2)多发结节构成比女性较男性略高(P<0.01);(3)不同性质结节的构成比在不同性别间无差异(P>0.05);(4)有结节组FT3、FT4水平较无结节组低,且有统计学差异(P<0.05,P<0.01),而TSH、TPOAb在两组间无差异(P>0.05)。结论:西宁地区查体人群甲状腺结节检出率38.5%,女性高于男性;多发结节构成比女性略高于男性,结节性质的构成比与性别无关;有结节组FT3、FT4水平较无结节组低。 Objective:The aim of this article is to investigate the prevalence and characteristics of thyroid nodule and its relationship with thyroid function among the physical examination population in Xining area and analyze the independent risk factors associated with thyroid nodules which may occur.Methods:A retrospective analysis of the survey was performed in the subjects who were on routine physical examination in Qinghai Province Hospital.All subjects underwent ultrasound thyroid scan,and the prevalence of thyroid nodule and its quantity,property and distribution were compared by different gender and age groups.The relationship between thyroid nodule existence and thyroid function was assessed.We adopted the method of multi-factor Logistic regression and analyzed the independent risk factors associated with thyroid nodules occurred.Results:(1)The study showed that the overall detection rate was 38.5%,which of female is higher than male(P〈0.01);(2)The proportion of multiple nodules was slightly higher in women than men(P〈0.01);(3)The composition ratio of thyroid nodules has nothing to do with the gender(P〉0.05);(4)FT3and FT4 levels of thyroid nodules group is lower than those without nodules with statistical significance(P〈0.05),and the difference of TSH and TPOAb levels between the two groups was not statistically significant(P〉0.05).Conclusion:Thyroid nodule detection rate is 38.5% by ultrasound examination among physical examination population in Xining area.The detection rate of female is higher than male.The proportion of multiple nodules is slightly higher among women than men and the composition ratio of thyroid nodules has nothing to do with the gender.FT3 and FT4levels of thyroid nodules group is lower than those without nodules.
机构地区 青海省人民医院
出处 《青海医药杂志》 2017年第4期2-5,共4页 Qinghai Medical Journal
基金 甲状腺结节诊疗新技术示范研究基金资助(基金编号:2014-SF-530)
关键词 西宁地区 查体人群 甲状腺结节 Xining area ; Physical examination population ; Thyroid nodules
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