摘要
In this work, an efficient and facile method for the preparation of 5-perfluoroalkylation uracils and uracil nucleosides through visible-light-mediated reaction has been developed. The reaction processes in high efficiency under mild reaction conditions and show broad substrate scope by employing commercial available perfluoroalkyl sources, thus demonstrates high potent application in life and medicinal science.
In this work, an efficient and facile method for the preparation of 5-perfluoroalkylation uracils and uracil nucleosides through visible-light-mediated reaction has been developed. The reaction processes in high efficiency under mild reaction conditions and show broad substrate scope by employing commercial available perfluoroalkyl sources, thus demonstrates high potent application in life and medicinal science.
基金
financially supported by the Young Talents Cultivation Program of the China Association for Science and Technology(No.2015-41)
The Training Programme Foundation for the Talents of the Zun Yi Science and Technology Bureau(No.201540)
Key Programs of Guizhou Province(125 Program,No.2015039)
The Natural Science Foundation of Jiangsu Province(No.BK20141265)
