摘要
目的探讨眼压设定在相对低的靶眼压范围情况下治疗白内障术后角膜水肿的临床疗效及预防措施。方法收集2014年1月至2016年12月期间于本院就诊的2466例白内障手术患者,其中术后发生角膜水肿的198例(198眼)患者做为研究对象,随机分为对照组和观察组,每组99例。对照组1、2级水肿常规给予典必殊眼水、左氧氟沙星眼水及复方托吡卡胺眼水点眼,3、4级角膜水肿在2级水肿治疗基础上加用50%高渗糖频繁点眼及地塞米松球结膜下注射,此组各级角膜水肿患者的眼压不超过21mm Hg不予处理。观察组:1、2级角膜水肿:给予典必殊眼水、左氧氟沙星眼水及复方托吡卡胺眼水,采取前房放液将眼压控制在9~12 mm Hg之间。3、4级角膜水肿:在1、2级水肿治疗的基础上加用典必殊眼膏,球结膜下注射地塞米松,同时将眼压应用前房放液或加用降眼压眼水将眼压控制在9~12 mm Hg之间。于术后第1、3、7、10、15~30天比较两组角膜水肿的恢复情况。结果观察组患者设定靶眼压配合治疗后患者角膜水肿恢复时间均比对照组快,其差异具有统计学意义(P<0.05)。对照组很多患者应用高渗剂点眼后出现异物感、眼疼等不适。结论白内障术后角膜水肿者给予设定靶眼压配合治疗后,角膜恢复更快、更好的减轻了患者的身心痛苦同时也减少了医患矛盾的发生。
Objective To investigate the clinical efficacy and preventive measures of corneal edema after cataract surgery with target intraocular pressure. Methods From January 2014 to December 2016,2466 cases of cataract surgery were performed in our hospital,of which 198 patients（ 198 eyes） with corneal edema were studied,randomly divided into control group and observation group,99 cases in each group. The control group 1,2 level of edema treated with Tobra Dex eye water,levofloxacin eye water,3,4 level of corneal edema on the basis of routine treatment combined with 50% hypertonic glucose and dexamethasone eyedrops frequent subconjunctival injection,the patients at all levels of intraocular pressure is less than 21 mm Hg without treatment of edema. The observation group： 1 and 2 grade edema treated with Tobra Dex and conventional topical levofloxacin eye water,3,4 level of corneal edema and dexamethasone ball on the basis of routine treatment of subconjunctival injection,all patients in the observation group were used to put liquid or anterior chamber intraocular pressure IOP lowering the intraocular pressure maintained in the eye water between 9 ~ 12 mm Hg. After first,3,7,15 ~ 30 days,corneal edema recovery in the two groups was compared between the 10 groups. Results The study showed that the recovery time of corneal edema in the observation group was higher than that of the control group after the target intraocular pressure matching therapy,the difference was statistically significant. The control group treated with hypertonic agent after many eye foreign body sensations,eye pain and other discomfort. Conclusions After cataract surgery,corneal edema patients are treated by setting target intraocular pressure,corneal recovery is faster,corneal recovery faster,which can relieve the patient ＇ s physical and mental pain,and reduce the contradiction between doctors and patients.
作者
马欣欣
朱彤
赵剑
Ma Xinxin et al(Department of Ophthalmology, the Third Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China)
出处
《齐齐哈尔医学院学报》
2017年第12期1409-1411,共3页
Journal of Qiqihar Medical University
关键词
白内障术后
角膜水肿
设定靶眼压
疗效
After cataract surgery
Corneal edema
Setting target intraocular pressure
Curative effect
