摘要
目的:利用水脂混合液模型评估多回波肝脏内插容积激发(mLIVE)技术定量分析脂肪含量的可行性和准确性。方法:制作水脂混合液模型,脂肪含量(容积比)分别为5%、10%、15%、20%、30%和40%,在国产超导1.5 T磁共振下用mLIVE序列测定模型脂肪含量,对测得的结果和真实脂肪含量做线性回归分析,分析两者相关性。以实际脂肪含量为标准,采用Bland-Altman散点图得出mLIVE测量值差值的95%可信区间的一致性界限,评估两者一致性。结果:mLIVE测得的脂肪含量和真实脂肪含量具有高度正相关关系(线性回归方程为y=0.810 6x+0.304 9,r^2=0.998 8,F=322 3,P=0.000)。Bland-Altman散点图得到的mLIVE测量值与实际脂肪含量差值的95%可信区间为-1.4%~8.4%。结论:mLIVE定量评价水脂模型中脂肪含量是可行的。
Objective To validate the feasibility and accuracy of multi echo liver interpolated volume excitation （mLIVE） in the quantification of fat content using fat-water mixture model.Methods Fat-water mixture phantom consisting of known fat fractions （v/v） of 5%,10%,15%,20%,30% and 40%,respectively,were established.The fat content of the established phantom were examined using mLIVE on a domestic 1.5 T magnetic resonance scanner.The relationships between measured fat fractions and known fat fractions were assessed using linear regression analysis,Taking the known fat fractions as the standards,we applied Bland-Altman map to obtain the consistency boundary of 95% confidence interval （95% CI） of the differences between measurements and known values and to assess their consistency.Results The fat fractions measured using mLIVE had a highly positive correlation with known fat-fractions （y=0.810 6x＋0.304 9,r^2=0.998 8,F=3 223,P=0.000）.According to Bland-Altman map,the 95%CI of differences between the results measured with mLIVE and known fat fraction ranged from-1.4% to 8.4%.Conclusion mLIVE can be used to quantify the fat content of fat-water mixture phantoms.
作者
李振玉
王娟
刘斌
彭保成
马园
LI Zhenyu WANG Juan LIU Bin PENG Baocheng MA Yuan(Xinxiang Central Hospital, Xinxiang 453000, Chin)
出处
《中国医学物理学杂志》
CSCD
2017年第5期468-471,共4页
Chinese Journal of Medical Physics
关键词
多回波肝脏内插容积激发
磁共振成像
脂肪
对比研究
multi echo liver interpolated volume excitation
magnetic resonance imaging
fat
comparative examination
