摘要
桥本甲状腺炎(HT)起病隐匿,病情迁延难愈。病变的甲状腺组织多呈弥漫性肿大,质韧如橡皮样,患者常出现梗阻感或颈部压迫感。血清中抗甲状腺过氧化物酶抗体(TPOAb)和(或)抗甲状腺球蛋白抗体(TGAb)滴度明显增高。因本病初期可无症状,后期出现甲状腺机能减退才得到确诊。其发病机制与遗传、环境、性别、细胞凋亡、免疫等有关。
Onset of Hashimoto＇s thyroiditis（HT） is concealed, the disease is prolonged, persistent refractory. Lesions of the thyroid tissue are diffuse enlargement, tough texture, such as rubber, often in patients with obstruction or neck compression. Antithyroid peroxidase antibodies（TPOAb） and（or） antithyroglobulin antibody（TGAb） drop significantly higher in serum. Because of the disease can be asymptomatic in the early, not diagnosed until to appear hypothyroidism in the last.The pathogenesis is related to heredity, environment, sex, cell apoptosis, immuneand so on.
作者
刘莹
李昀昊
杨宏杰
LIU Ying LI Yunhao YANG Hongjie(Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China)
出处
《长春中医药大学学报》
2017年第4期686-688,共3页
Journal of Changchun University of Chinese Medicine
基金
上海市科委中医优势学科基金(12401904800)
关键词
桥本甲状腺炎
发病机制
遗传
环境
细胞凋亡
Hashimoto＇s thyroiditis
pathogenesis
heredity
environment
cell apoptosis
