摘要
目的分析乙型肝炎病毒DNA(HBV-DNA)与血清标志物的检测结果。方法随机选取鹤壁市人民医院门诊及住院部在2014年1月—2015年10月期间收治的123例乙型肝炎病毒感染患者在检验科检查作为观察对象,采用荧光定量PCR检测方法对123例患者HBV-DNA水平进行检测,同时采用酶联免疫法对血清标志物(HBV-M)进行检查,分析乙型肝炎病毒DNA与血清标志物的检测结果。结果 123例乙型肝炎患者中,共78例HBe Ag阳性标本,45例HBe Ag阴性标本;78例HBe Ag阳性标本HBV-DNA阳性率为100.0%,HBe Ag阴性标本HBV-DNA阳性率为24.44%,2种HBe Ag标本HBV-DNA阳性率差异有统计学意义(P<0.05)。结论乙型肝炎患者病HBV-DNA阳性率与血清标志物(HBV-M)密切相关,开展相关检测,对判断患者体病乙肝病毒复制情况具有推动作用。
Objective To analysis of hepatitis B virus DNA（HBV-DNA） and serum markers detection result. Methods A randomly selected Hebi City People＇s hospital outpatient and inpatient department in January 2014- October 2015 from 123 patients with hepatitis B virus infection patients examined in laboratory check as the observation object, using fluorescence quantitative PCR detection method for detection of HBV-DNA levels in 123 patients. At the same time,the enzyme immunoassay of serum markers（HBV-M） were examined, hepatitis hepatitis virus DNA and serum markers of detection results analysis. Results A total of 123 cases In patients with hepatitis B, a total of 78 patients with HBe Ag positive samples, 45 patients with HBe Ag negative specimens; 78 cases of HBe Ag positive samples HBV-DNA positive rate of 100.0%, HBe Ag negative specimens positive rate of HBV-DNA was 24.44%. Two specimens of HBe Ag positive rate of HBV-DNA with significant difference（P 〈0.05）. Conclusion Hepatitis B patients with HBV-DNA positive rate and serum sign（HBV-M） is closely related to carry out related testing, to determine in patients with hepatitis B virus replication has a role in promoting.
出处
《系统医学》
2016年第4期10-11,14,共3页
Systems Medicine
