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罗哌卡因联合醋酸曲安奈德在膝关节镜下半月板手术后的镇痛作用 被引量:3

The dual analgesic effect of ropivacaine and triamcinolone acetonide after knee arthroscopic surgery on meniscus
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摘要 目的探讨罗哌卡因联合醋酸曲安奈德在膝关节镜下半月板手术后镇痛中的作用。方法将70例单侧膝关节镜下半月板手术患者按治疗方法分为干预组(注入罗哌卡因+醋酸曲安奈德,35例)和对照组(注入罗哌卡因,35例)。比较两组患者术后1、3、6、12、24、48 h疼痛VAS评分及不良反应。结果所有患者术后48 h内未发现明显不良反应。干预组术后1、3、6、12 h各时间点的VAS评分均低于对照组(P<0.05),24 h后的VAS评分两组差异无统计学意义(P>0.05)。两组患者术后12 h出现VAS评分最大值,但干预组低于对照组(P<0.05)。干预组术后48 h内追加镇痛药物患者数量明显低于对照组(P<0.05)。结论罗哌卡因联合醋酸曲安奈德可以有效减轻膝关节镜下半月板手术后疼痛,具有操作简单、安全性高的优点。 Objective To investigate the dual analgesic effect and safety of ropivacaine and triamcinolone acetonide after knee arthroscopic surgery on meniscus. Methods The 70 patients with half knee arthroscopic surgery on menis-cus were retrospectively analyzed. They were divided into intervention group ( ropivacaine and triamcinolone ace-tonide, 35 cases) and control group ( ropivacaine,35 cases) by therapy methods. The visual analogue score (VAS) and adverse reactions were recorded at 1,3,6,12,24,48 h. Results All patients had no serious complications were found in 48 h postoperatively. The intervention group had lower VAS at 1 ,3,6,12 h compared with the control group (P 〈 0. 05 ) . No significant difference was found between these groups after 24 h postoperatively ( P 〉 0. 05 ) . The VAS in both groups increased rapidly and peaked 12 h postoperatively, while the intervention group had lower VAS (P 〈 0. 05) . The patients needed rescue analgesia at 48 h postoperatively was less in intervention group (P 〈0. 05). Conclusions Analgesia is more effective, and safety with the combination of ropivacaine and triamcinolone acetonideafter knee arthroscopic surgery on meniscus.
出处 《临床骨科杂志》 2017年第4期466-468,共3页 Journal of Clinical Orthopaedics
基金 江苏省科技厅临床医学科技专项基金(编号:BL2012002)
关键词 罗哌卡因 醋酸曲安奈德 膝关节镜检查 半月板手术 镇痛 ropivacaine triamcinolone acetonide knee arthroscopy meniscus surgery analgesia
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