摘要
研究犬急性胰腺炎模型的建立与手术治疗方法。采用胆总管末端结扎术建立急性胰腺炎动物模型并探讨手术方法治疗效果。结果表明,术后第1天,犬血清淀粉酶值升高为2 102 u/L,血糖值升高为7.8 mmol/L,血清钙值降低为2.0 mmol/L,尿中出现葡萄糖,并伴有腹部剧痛、剧烈呕吐等典型的急性胰腺炎临床症状,表明模型建立成功。采用手术方法进行治疗,术后第4天,实验动物临床症状明显减轻,各项生化指标基本恢复至正常水平。表明采用胆总管末端结扎术模型建立成功,手术方法治疗急性胰腺炎效果好,为犬急性胰腺炎模型的建立和手术治疗提供了一定参考。
For studying canine acute pathogenesis and treatment of acute pancreatitis, common bile duct ligation was used to establish an animal model of acute pancreatitis and the effect of surgical treatment was investigated. The results showed that the level of amylase concentration was increased to 2 102 u/L, the level of blood sugar was increased to 7.8 mmol/L and the level of calcium was decreased to 2.0 mmol/L on 1st after surgery with high fever and vomiting of the acute pancreatitis. Experimental animal clinical symptoms significantly reduced and indexes returned to normal on 4th. The results revealed that common bile duct ligation model was successfully established, and the effect of surgical treatment of acute pancreatitis was good, which could provide reference to build canine acute pathogenesis model and surgical treatment.
作者
高宇航
GAO Yuhang(College of Veterinary Medicine, Gansu Agricultural University, I.anzhou Gansu 730070, Chin)
出处
《中兽医医药杂志》
2017年第4期5-8,共4页
Journal of Traditional Chinese Veterinary Medicine
基金
甘肃农业大学教研产学支持计划
关键词
犬
急性胰腺炎
模型建立
手术治疗
canine
acute pancreatitis
modeling
surgical treatment
