摘要
目的分析输尿管下段结石体外冲击波碎石术后坦索罗辛和索利那新辅助排石的治疗效果。方法选择我院2013年3月至2016年10月行输尿管下段结石体外冲击波碎石术治疗的100例患者作为研究对象,随机分为试验组及对照组,各50例。对照组行索利那新辅助排石,试验组行坦索罗辛联合索利那新辅助排石。对比两组患者的临床疗效。结果试验组患者的结石排净率为96.00%,明显高于对照组的80.00%(P<0.05);试验组患者的结石排出时间为(3.01±2.20)d,明显短于对照组的(6.50±2.20)d(P<0.05);试验组0、1、2级疼痛发生率均明显优于对照组(P<0.05);两组均未发生严重不良反应。结论输尿管下段结石患者体外冲击波碎石术后行坦索罗辛和索利那新辅助排石,可以提高排石成功率、加速排石,降低患者疼痛程度且无明显药物不良反应。
Objective To analyze the effect of tamsulosin combined with solifenacin on assisting remove calculus on distal ureteral calculus after extracorporeal shock wave lithotripsy （ESWL）. Methods A total of 100 cases of patients with distal ureteral calculus underwent ESWL from March 2013 to October 2016 were selected as the study objects. They were randomly divided into experimental group and control group, with 50 cases in each group. The control group was treated with solifenacin and the experimental group was treated with tamsulosin and solifenacin to assisting remove urinary calculus. The clinical efficacy of the two groups were compared. Results The stone removal rate was 96.00% in the experimental group, which was significantly higher than 80.00% in the control group （P〈0.05）. The exclusion time of stones in the experimental group was （3.01±2.20） d, which was significantly shorter than （6.50±2.20） d in the control group （P〈 0.05）. The incidences of pain at grade 0, grade 1 and grade 2 in the experimental group were significantly better than those in the control group （P〈0.05）; there was no serious adverse effect in the two groups. Conclusion For patients with distal ureteral calculus after ESWL, tamsulosin and solifenacin assisting remove calculus can reduce the success rate of stone removal, accelerate the row of stone, and reduce the pain degree, with no obvious adverse drug reaction.
出处
《临床医学研究与实践》
2017年第24期59-60,共2页
Clinical Research and Practice
关键词
输尿管下段结石
体外冲击波碎石
坦索罗辛
索利那新
distal ureteral calculus
extraeorporeal shock wave lithotripsy （ESWL）
tamsulosin
solifenacin
