摘要
目的分析急性加重期慢性阻塞性肺疾病(COPD)合并2型糖尿病(T2DM)患者的临床特征,为临床制定合理的治疗方案提供依据。方法选取该院2010年5月—2016年5月收治的48例急性加重期COPD合并T2DM患者作为研究对象,同时选取同期48例未合并T2DM的急性加重期COPD患者作为对照,对两组患者的临床资料进行回顾性分析。结果 COPD合并T2DM组呼吸衰竭、真菌感染、混合感染发生率分别为45.83%、33.33%、62.50%,均显著高于单纯COPD组(P<0.05);COPD合并T2DM组每年急性加重次数、平均住院日、平均治疗费用均明显多于单纯COPD组(P<0.01);COPD合并T2DM组患者的PaO_2水平、FEV1%预计值、FEV1/FVC均明显低于单纯COPD组(P<0.01),Pa CO2水平明显高于单纯COPD组(P<0.01)。结论与单纯急性加重期COPD患者相比,合并T2DM后患者的病情更严重、肺功能及血气分析更差。
Objective To analyze the clinical features of patients with acute exacerbations of chronic obstructive pulmonary disease and type 2 diabetes and provide basis for the rational formulation of treatment plan in clinic. Methods 48 cases of patients with COPD and T2DM in our hospital from May 2010 to May 2016 were selected as the research objects and 48 cases of patients with COPD without T2DM at the same period were selected as the control group, and the clinical data of the two groups were reviewed. Results The incidence rate of respiration failure, fungal infection and mixture infection of patients in the combination group was respectively 45.83%, 33.33% and 62.50%, which was obviously higher than those in the simple COPD group （P〈0.05）, the acute exacerbation time per year, average length of stay and average treatment expense in the combination group was obviously lower than those in the simple COPD group （P〈0.01）, The level of PaO2, FEV1% and FEV1/FVC in patients with COPD combined with T2DM were significantly lower than those in group COPD （P〈0.01）, and the PaCO2 level was obviously higher than that in the simple COPD group（P〈0.01 ）. Conclusion The disease of patients with COPD with T2DM is more serious than the patients with simple acute exacerbation, and the lung function and blood gas analysis is worse.
出处
《系统医学》
2017年第4期62-64,共3页
Systems Medicine
关键词
慢性阻塞性肺疾病
急性加重期
2型糖尿病
临床分析
Chronic obstructive pulmonary disease
Acute exacerbation
Type 2 diabetes
Clinical analysis
