摘要
涎腺腺样囊性癌是最常见的唾液腺恶性肿瘤之一,其临床特点表现为病程缓慢,沿神经侵袭性进展,并伴有远处转移,预后较差,远期生存率较低。转化生长因子β1(transforming growth factor-β1,TGF-β1)曾在多种肿瘤中被高表达检出,与肿瘤的发生发展、转移等生物学行为存在密切关系,为未来肿瘤治疗提供新的目标靶点。
Salivary adenoid cystic carcinoma（ SACC） is one of the most common malignant salivary gland tumors and its clinical manifestations are slow growth,perineural invasion and potential local recurrence. Along with distant metastasis,its prognosis is poor and long-term survival rate is low. Transforming growth factor beta 1（ TGF-β1） is highly expressed in a wide variety of tumors and there is a close relationship with the detection,development,and metastasis of tumor biology behaviors,which can be regarded as new targets for the future tumor treatment.
出处
《现代肿瘤医学》
CAS
2017年第18期2997-3000,共4页
Journal of Modern Oncology
基金
国家自然科学基金(编号:81672827)
