摘要
目的观察罗哌卡因复合芬太尼或右美托咪定关节腔注射用于膝关节镜术后镇痛的效果。方法择期行膝关节镜手术患者50例随机均分为两组,RF组关节腔注射含芬太尼50μg的0.25%罗哌卡因混合液20ml,RD组关节腔注射含右美托咪定1μg/kg的0.25%罗哌卡因混合液20ml。记录患者术后2、4、6、8、10和12h静息时和活动时VAS疼痛评分,比较两组术后24h内布托啡诺用量和不良反应发生情况。结果两组术后10h内各时间点静息时和活动时VAS疼痛评分均较低,但两组比较无统计学差异(P>0.05);两组术后24h内布托啡诺用量无统计学差异(P>0.05)。两组均未见明显不良反应。结论罗哌卡因复合芬太尼或右美托咪定关节腔注射均能提供良好的膝关节镜术后镇痛。
Objective To evaluate the efficacy of intra-articular injection of ropivacaine mixed with fentanyl or dexmedetomidine for postoperative analgesia after arthroscopic knee surgery.MethodsFifty patients underwent selective arthroscopic knee surgery were randomly and equally assigned into two groups.Group RF received fentanyl 50μg and 0.25% ropivacaine and group RD received dexmedetomidine 1μg/kg and 0.25% ropivacaine,which were intra-articularly injected in a total volume of 20ml.VAS pain scores at rest and on movement were evaluated at 2,4,6,8,10 and 12 hours after surgery.The consumption of butorphanol in 24 hours after surgery was calculated.The adverse effects were observed.Results VAS pain scores at rest and on movement at all time points in 10 hours were lower in two groups,which were not significantly different between two groups（P〉0.05）.The consumption of butorphanol in 24 hours after surgery in group RF was similar to that in group RD（P〉0.05）.No obvious adverse effects were seen in two groups.Conclusion Intra-articular injectrion of ropivacaine combined with fentanyl or dexmedetomidine can provide an effective postoperative analgesia in the patients underwent arthroscopic knee surgery.
出处
《江苏医药》
CAS
2017年第14期1007-1010,共4页
Jiangsu Medical Journal
关键词
罗哌卡因
芬太尼
右美托咪定
膝关节镜手术
术后镇痛
Ropivacaine
Fentanyl
Dexmedetomidine
Arthroscopickneesurgery
Postoperativeanalgesia
