摘要
目的分析抗菌药物相关性腹泻的发病情况,为临床制订有效的预防控制措施提供依据。方法回顾性分析2015年全年的抗菌药物相关性腹泻住院患者76例病例,并进行帕累托图分析。分析抗菌药物相关性腹泻的易患因素、抗菌药物使用情况、临床症状、实验室检查以及治疗和转归。结果抗菌药物相关性腹泻多发生于老年人,抗菌药物使用时间超过7 d,联合使用广谱抗菌药物腹泻感染率较高。给予停药、微生态制剂及对症治疗大多有效。结论如果患者使用抗菌药物期间或之后短时间内出现腹泻要考虑抗菌药物相关性腹泻。合理使用抗菌药物,严格控制广谱抗菌药物的使用是预防、控制抗菌药物相关性腹泻的关键。
Objective To analyze the incidence of antibiotic associated diarrhea（ AAD）,and to provide evidence for the effective prevention and control measures. Methods The retrospective pareto diagram analysis was played on 76 patients with AAD in 2015. The risk factors, the use of antibiotics, clinical symptoms, laboratory examination, treatment and prognosis of AAD were analyzed. Results AAD frequently occurred in the elderly,the use time of antibiotics was more than 7 days,the combined use of broad-spectrum antimicrobial drugs had higher infection rate of diarrhea. Withdrawal of the drug, giving probiotics and symptomatic treatment were mostly effective. Conclusion AAD should be considered if the diarrhea occurred in a short period of time during or after the use of antibiotics. Rational use of antibiotics,strict control of the use of broad-spectrum antibiotics is the key to prevent and control the AAD.
作者
马超
李春钰
崔喜凤
张树荣
Ma Chao Li Chunyu Cui Xifeng Zhang Shurong(Department of Pharmacy, Beijing Fengtai Hospital, Beijing, China 100071)
出处
《中国药业》
CAS
2017年第11期86-88,共3页
China Pharmaceuticals
关键词
抗菌药物相关性腹泻
帕累托图
预防
antibiotic associated diarrhea
pareto diagram
prevention
