摘要
目的:探讨同型半胱氨酸(Hcy)、C反应蛋白(CRP)、纤维蛋白原(FIB)等与2型糖尿病合并抑郁症的关系。方法:选取我院2015年6月—2017年2月收治的2型糖尿病(T2DM)患者160例,抑郁症诊断用汉密尔顿抑郁量表评分(HAMD-17)确定。分为T2DM合并抑郁症(T2DM+DEP.)组59例,T2DM未合并抑郁症(T2DM-non-DEP.)组101例。比较两组Hcy、CRP、FIB、空腹血糖(FBG)等指标,计算HAMD-17评分与Hcy、CRP、FIB、FBG的相关性。结果:T2DM+DEP.组Hcy、CRP、FIB、FBG较T2DM-non-DEP.组增高(P<0.01或P<0.05),HAMD-17评分与FBG、Hcy、CRP、FIB具有相关性(P<0.01或P<0.05)。结论:T2DM合并抑郁症的发生可能是多因素作用的结果,Hcy、CRP、FIB、血糖可能参与了T2DM合并抑郁症的发病过程。
Objective： To investigate the relationship between serum level of homocysteine（Hcy）, C-reactiveprotein （CRP）,Fibrinogen（FIB）. Methods： 160 cases of type 2 diabetes were divided into two groups by Hamilton depression scale. Measure fasting blood glucose（FBO）, serum level of homoeystein,C-reactive protein（CRP）, Fibrinogen. Results： The levels of Hcy, CRP, FIB and FPG in groups of type 2 diabetes with depression are higher than those in groups without depression, the HAMD score and Hey,CRP, FIB and FBG were positively correlated, the differences were sta- tistically significant（P〈0. 05 or 0. 01）. Conelusion： T2DM with depression is resulted from many factors including the levels of FBG, Hey, CRP, FIB.
作者
邵岩
丁怀莹
赵建美
张滕
SHAO Yan DING Huaiying ZHAO Jianmei et al(Department of Second Internal Medicine, Tianjin Traditional Chi- nese Medicine Hospital in Binhai New Area 300451)
出处
《医学理论与实践》
2017年第15期2190-2191,共2页
The Journal of Medical Theory and Practice
基金
天津市科技计划项目(合同编号:15ZXLCSY00020)
