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雾化吸入糖皮质激素用于长期控制不佳的老年哮喘疗效分析 被引量:9

Clinical Efficacy of Atomizing Inhaled Glucocorticoid in Elderly Patients with Poor Long-Term Asthma Control
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摘要 目的观察老年哮喘长期控制不佳应用雾化吸入糖皮质激素的疗效。方法选取医院2014年7月至2016年7月收治的老年哮喘患者98例,随机分为试验组与对照组,各49例。试验组采用雾化吸入糖皮质激素治疗,对照组采用常规治疗,对比两组患者的疗效与不良反应。结果试验组患者的呼气峰流速变化值明显优于对照组患者,差异有统计学意义(P<0.05);试验组患者哮喘控制测试(ACT)评分显著高于对照组患者,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异有统计学意义(P<0.05)。结论雾化吸入糖皮质激素治疗老年哮喘效果明显、安全性较高,值得临床推广。 Objective To analyze clinical efficacy of atomizing inhaled glucocorticoid in elderly patients with poor long-term asthma control. Methods Totally 98 elderly patients with asthma in our hospital from July 2014 to July 2016 were randomly divided into the experimental group and the control group,49 cases in each group. The experimental group was taken atomizing inhaled glucocorticoid,the control group was treated with conventional method. The therapeutic effect and adverse reactions in the two groups were compared. Results The peak expiratory flow rate of the experimental group was significantly better than that of the control group (P 〈 0. 05),the ACT scores of the experimental group was significantly higher than that of the control group( P 〈 0. 05),the adverse reactions in the two groups had significant difference(P 〈 O. 05). Conclusion The clinical efficacy of atomizing inhaled glucocorticoid in elderly patients with poor long- term asthma control is good,it is safe and worthy of clinical promotion.
作者 钟兴峰 Zhong Xingfeng(Department of Respiratory, Macheng People's Hospital, Huanggang, Hubei, China 43800)
出处 《中国药业》 CAS 2017年第10期54-56,共3页 China Pharmaceuticals
关键词 雾化吸入 糖皮质激素 哮喘 老年 临床疗效 aerosol inhalation glucocorticoid asthma elderly clinical effect
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