摘要
目的 探讨心房颤动（AF）患者心外膜脂肪组织（EAT）体积与首次射频消融术后空白期AF复发的相关性。方法 回顾性分析85例AF患者的临床资料，采用螺旋CT检测EAT体积；首次射频消融术后随访6~18个月，其中空白期AF复发27例（观察组），空白期无AF复发58例（对照组），比较两组EAT体积并进行相关性分析。结果 观察组总EAT体积、左心房周EAT体积明显高于对照组[（118.6 ± 29.2）cm3比（94.3 ± 27.1）cm3和（28.9 ± 9.0）cm3比（22.7 ± 7.3）cm3]，差异有统计学意义（P〈0.05）。多元Logistic回归分析结果显示，总EAT体积和左心房周EAT体积是预测RA术后空白期AF复发的独立因素（OR= 1.053和1.128，95% CI 1.010~1.079和1.032~1.224，P〈0.05）。观察组远期AF复发率明显高于对照组[40.7%（11/27）比15.5% （9/58）]，差异有统计学意义（χ2= 6.031，P〈0.05）。结论 当患者总EAT体积、左心房周EAT体积较大时，首次接受射频消融术后空白期更容易AF复发。
Objective To study the correlation of epicardium adipose tissue （EAT） volume with bland period atrial fibrillation （AF） recurrence after first radiofrequency ablation （RA）.Methods The clinical data of 85 patients with AF were retrospectively analyzed. The EAT volume was measured by CT scanning. The patients were followed up for 6-18 months after first RA. Among the patients, 27 cases were found to have bland period AF recurrence （observation group）, and 58 cases were not found to have bland period AF recurrence （control group）. The EAT volume of 2 groups was compared and analyzed.Results The total EAT volume and left atrial EAT volume in observation group were significantly higher than those in control group： （118.6 ± 29.2） cm3 vs. （94.3 ± 27.1） cm3 and （28.9 ± 9.0） cm3 vs. （22.7 ± 7.3） cm3, and there were statistical differences （P〈0.05）. The multivariate Logistic regression analysis result showed that total EAT volumes and left atrial EAT volumes were the independent risk factors for blank period AF recurrence （OR= 1.053 and 1.128, 95% CI 1.010-1.079 and 1.032-1.224, P〈0.05）. The AF incidence of long-term recurrence in observation group was significantly higher than that in control group： 40.7% （11/27） vs. 15.5% （9/58）, and there was statistical difference （χ2= 6.031, P〈0.05）.Conclusions The AF is easier to recur during blank period after first RA in AF patients with a larger total EAT volume and a larger left atrial EAT volume.
出处
《中国医师进修杂志》
2017年第7期630-633,共4页
Chinese Journal of Postgraduates of Medicine
关键词
心房颤动
导管消融术
复发
心外膜脂肪组织
Atrial fibrillation
Catheter ablation
Recurrence
Epicardium adipose tissue
