摘要
目的:系统评价玉液汤治疗2型糖尿病的临床疗效,为临床治疗提供循证依据。方法:通过计算机检索Pubmed、CNKI、VIP、万方医学网收集运用玉液汤临床文献,时间限制为建库至2014年9月1日,提取资料进行质量评价后,采用Rev Man5.3软件进行meta分析。结果:共纳入9个RCT,共756名患者。Meta分析结果显示:运用玉液汤治疗后患者糖尿病的症状、体征、血糖改善的显效性(OR=1.97,95%CI:1.46~2.66,Z=4.46,P<0.00001)、总有效率(OR=4.82,95%CI:3.06~7.59,Z=6.78,P<0.00001),均显著优于对照组,2组比较差异有统计学意义。结论:玉液汤治疗2型糖尿病有效。上述结论尚待进一步开展更多大样本、高质量研究予以证实。
Objective：To evaluate the clinical effect of Yuye decoction in the treatment of type 2 diabetes with an attempt to pro- vide evidences for the clinical treatment. Methods：Major online databases including PUBMED,CNKI, VIP, and Wan Fang medical network were searched for a period between the time that the database were built to 2014 09 01 to collect RCT studies on Yuye de- coction in treatment of type 2 diabetes. Data were extracted for quality evaluation and analyzed by RevMan 5.3 software. Results ： Nine RCT trials were included. A total of 756 subjects were enrolled. The recta-analysis showed that applying Yuye decoction in treatment of type 2 diabetes had effective value in improving symptoms and signs [ R = 1.97,95% CI ： 1. 46 - 2.66 ,Z =4.46 ,P 〈 0. 00001 ], total effective rate [OR = 4.82, 95% CI：7.59 - 3.06, Z = 6.78, P, 0. 00001 ], which were remarkably higher than those of the control groups, with significant difference between control groups. Conclusion：Yuye Decoction was effective in the treatment of type 2 diabetes mellitus. The above conclusions still need further study in carrying out more large samples and confir- ming high quality studies.
出处
《世界中医药》
CAS
2017年第3期680-683,共4页
World Chinese Medicine
基金
广西名老中医民族医传承工作室建设项目桂卫中[2014]9号文件
广西省自然科学基金项目(编号:2015GXNSFAA139119)
关键词
玉液汤
2型糖尿病
消渴
有效性
META分析
Yuye decoction
Type 2 diabetes
Consumptive thirst
Effect
Meta^analysis
