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拉贝洛尔治疗重度子痫前期患者的疗效观察

Effect of labetalol in treatment of severe preeclampsia
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摘要 目的探讨拉贝洛尔治疗重度子痫前期临床应用效果。方法对照组重度子痫前期患者给予临床常规治疗,研究组在常规治疗基础上加用拉贝洛尔,2组重度子痫前期患者均连续治疗7 d为宜。结果治疗后2组DBP、SBP、HR、24 HUP均较之前显著降低,研究组上述指标改善效果更优(P〈0.05)。研究组重度子痫前期患者早产率、产后出血率、新生儿窒息率(分别为10.20%、8.16%、6.12%)均显著低于对照组(28.57%、34.69%、20.41%)(P〈0.05)。结论应用常规治疗基础上加用拉贝洛尔可显著提高重度子痫前期降压效果,有利于保障母婴身心健康、生命安全。 Objective To investigate the effect of labetalol in treatment of severe preeclampsia clinical effect. Methods The control group of severe preeclampsia patients received routine clinical treatment,the study group were treated with labetalol,two groups of patients with severe preeclampsia were treated for 7 d. Results After treatment,the two groups of DBP,SBP,HR,and 24 HUP were significantly lower than before,the study group improved the above indicators better( P〈 0. 05). The study group of patients with severe preeclampsia premature delivery rate,postpartum hemorrhage rate,neonatal asphyxia rate( 10. 20%,8. 16%,6. 12%) were significantly lower than the control group( 28. 57%,34. 69%,20. 41%)( P〈 0. 05). Conclusion The application of conventional therapy combined with labetalol can significantly improve the hypotensive effect of severe preeclampsia,is conducive to the protection of maternal physical and mental health and life safety.
出处 《中国生化药物杂志》 CAS 2017年第7期274-275,共2页 Chinese Journal of Biochemical Pharmaceutics
关键词 重度子痫前期 拉贝洛尔 妊娠结局 应用效果 severe preeclampsia labetalol pregnancy outcome application effect
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