摘要
目的观察水针刀结合通痹酊剂加热敷对膝骨关节病的血沉、CRP、IL-1的因素的影响。方法 96例膝骨关节病患者按治疗方式均分为对照组与实验组（n=48）,对照组选用水针刀治疗,实验组在水针刀基础上结合通痹剂加热敷治疗,均持续治疗14天。观察2组临床疗效,CRP、IL-1、血沉、膝关节功能损伤评分及安全性。结果实验组总有效率93.75%高于对照组79.17%（P〈0.05）。治疗后,实验组CRP、IL-1、血沉低于对照组[（7.09±0.97）mg/L、（6.54±0.82）ng/L、（16.47±2.03）mm/h比（10.35±1.28）mg/L、（7.21±0.93）ng/L、（18.25±2.21）mm/h]（P〈0.05）。实验组膝关节功能损伤评分较对照组高（P〈0.05）。2组安全性比较差异无统计学意义。结论水针刀结合通痹剂加热敷治疗膝骨关节病的临床疗效优于水针刀,能够促进炎症的吸收,缓解膝关节功能。
Objective To observe the effect of injection needle scalpel combined with Tongbi tincture heat deposited on the erythrocyte sedimentation rate,CRP and IL-1 in knee osteoarthritis. Methods 96 cases of knee osteoarthrosis according to the treatment divided into the control group（ n = 48） and experimental group（ n = 48）,the control group was treated with injection needle scalpel,the experimental group on the basis of injection needle scalpel combination of tongbi tincture heat deposited,all lasted for 14 days. The clinical efficacy,CRP,IL-1,blood sink,knee joint functional impairment score,and safety was observed in the two groups. Results The total effective rate of the experimental group was 93. 75%,higher than the control group 79. 17%（ P 〈0. 05）. After treatment,the CRP,IL-1,blood sedimentation of experimental group was lower than the control group[（ 7. 09 ± 0. 97） mg/L,（ 6. 54 ± 0. 82） ng/L,（ 16. 47 ± 2. 03） mm/h vs.（ 10. 35 ± 1. 28） mg/L,（ 7. 21 ± 0. 93） ng/L,（ 18. 25 ± 2. 21） mm/h]（ P 〈0. 05）. The scores of knee joint function impairment in the experimental group was higher than that in the control group（ P〈 0. 05）. There was no significant difference in safety between the two groups. Conclusion The therapeutic effect of injection needle scalpel combined with Tongbi tincture heat deposited in treatment knee osteoarthrosis is better than injection needle scalpel. It can promote the absorption of inflammation,relieve knee function.
出处
《中国生化药物杂志》
CAS
2017年第7期138-140,143,共4页
Chinese Journal of Biochemical Pharmaceutics
基金
温州市公益性社会发展医疗卫生科技项目(Y20160383)
关键词
膝骨关节病
水针刀
通痹酊剂加热敷
临床疗效
knee osteoarthrosis
injection needle scalpel
tongbi tincture heat deposited
clinical curative effect
