摘要
目的探讨血清镁对急诊危重患者生存状况的影响,为其临床研究提供可参考依据。方法选择80例我院急诊危重患者作为研究对象,详细记录患者信息,随访患者生存状况,筛选出影响患者生存状况的相关因素;同时根据血清镁水平分为低血镁组(滞留时间<0.7mmol·L-1),正常组(1.2mmol·L-1>滞留时间≥0.7mmol·L-1),高血镁组(滞留时间≥1.2mmol·L-1)。分析不同血镁水平对急诊重症患者生存状况的影响。结果 80例急诊危重患者中20例(25.0%)死亡或自动离院。死亡组患者年龄、SOFA评分、APACHEⅡ评分、急诊滞留时间均高于存活组,而血钠、血镁水平低于存活组,差异有统计学意义(P<0.05)。年龄大,入院SOFA评分及APACHEⅡ评分高,急诊滞留时间长,血镁水平低是影响急诊危重患者生存状况的危险因素(P<0.05)。80例急诊危重患者中有28例(35.0%)存在低血镁,12例(15.0%)存在高血镁,40例(50.0%)血清镁水平在正常范围。低血镁组生存率低于正常组与高血镁组,而SOFA评分、APACHEⅡ评分、住院时间及住院费用高于正常组与高血镁组,差异有统计学意义(P<0.05)。结论低血镁增加急诊重症患者死亡率,应重视急诊重症患者低血镁的发生。
OBJECTIVE To investigate the incidence of hypomagnesemia and the effect of serum magnesium levels on the prognosis of emergency critically ill patients. METHODS 80 emergency critically ill patients were in- cluded. The living conditions were followed up and all patients were divided into three groups: normomagnesemic group (serum magnesium levels 0. 7-1.2mmol·L^-1), hypomagnesemic group (serum magnesium levels 〈 0. 7mmol·L^-1) ,and hypermagnesemic group (serum magnesium levels 〉 1.2mmol·L^-1). The effect of serum magnesium levels were analyzed of emergency critically ill patients. RESULTS There were 20 patients (25.0%) died or auto- matic departure in 80 emergency critically ill patients. The age, SOFA score, APACHE 11 score and emergency de- partment length of stay in death patients were higher than that in survival group. The difference were statistically sig- nificant (P 〈 0. 05 ). The level of sodium and magnesium in death patients were lower than that in survival group. The difference were statistically significant ( P 〈 0. 05 ). Multiariable analysis found that elder, higher SOFA score and APACHE 11 score, prolonged emergency department length of stay, lower level of magnesium were the independent risk factors of death in emergency critically ill patients (P 〈 0.05). There were 28 patients (35.0%) with low magnesi- um,12 patients (15.0%) with high magnesium,40 patients (50.0%) with nomol magnesium. The survival rate in low magnesium group were lower than that in high magnesium group and nomol magnesium group. The difference were statistically significant ( P 〈 0. 05 ). The SOFA score and APACHE II score, length of hospital stay and cost of hospitalization in low magnesium group were higher than that in high magnesium group and nomol magnesium group. The difference were statistically significant (P 〈 0. 05). CONCLUSION Serum magnesium levels are closely related to mortality rate in emergency critically ill patients, so more attention should b
出处
《海峡药学》
2017年第7期88-91,共4页
Strait Pharmaceutical Journal
关键词
血清镁
急诊
重症
生存状况
Serum magnesium
Emergency
Critically ill
Living conditions