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急性一氧化碳中毒急救的研究进展 被引量:1

Research progress on emergency treatment of acute carbon monoxide poisoning
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摘要 急性一氧化碳中毒(ACOP)急救治疗主要包括氧疗、用药、并发症对症治疗与特殊患者的救治四个组成部分。高压氧疗是一线疗法,疗效肯定。治疗药物主要包括神经保护药物、自由基清除剂、促醒药醒脑静以及纳洛酮、糖皮质激素、脑细胞赋活剂、胞二磷胆碱、神经营养药B族维生素、抗血小板、扩血管药物等。血气分析是进行病情监护的重要方法,连续监测非常关键,仪器设备能够实时动态评价患者血气状态,用于分析高压氧疗的疗效。其他常用的指标还包括乳酸与乳酸清除率、血CK-BB动态变化等,影像学在ACOP迟发性脑病的预测以及诊断中也有较高的价值。ACOP疗效预测以及迟发性脑病的预测比较困难,不利于预防性治疗开展,尚需进一步的研究。 The emergency treatment of acute carbon monoxide poisoning(ACOP)includs four parts with oxygen therapy,medication,symptomatic treatment of complications and special treatment. Hyperbaric oxygen therapy is a first-line therapy with definite curative effect. Treatment drugs mainly include neuroprotective agents, free radical scavenger, agrypnotic awake brain static and naloxone,glucocorticoid,activating brain cells agent,cytoplasmic two choline,neurotrophic drugs B vitamins,antiplatelet agents,vasodilator drugs. Blood gas analysis is an important method for condition monitoring,continuous monitoring is the critical. The instrument can evaluate the blood gas status of the patients in real time,which is used to analyze the curative effect of hyperbaric oxygen therapy. Other commonly used indicators include lactate and lactate clearance rate,blood CK-BB dynamic changes,imageology with a higher value in the prediction and diagnosis of ACOP delayed encephalopathy. The efficacy prediction of ACOP and the prediction of delayed encephalopathy are difficult,which is not conducive to preventive treatment. Further studies are needed.
作者 杨继生
出处 《中国城乡企业卫生》 2017年第7期12-14,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
关键词 急性一氧化碳中毒 急救 进展 Acute carbon monoxide poisoning First aid Progress
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