摘要
目的:探讨米非司酮配伍米索前列醇用于10～14周妊娠的临床应用效果。方法:对停经10～14周要求终止妊娠且无用药禁忌证的孕妇采用口服米非司酮和阴道后穹窿放置米索前列醇进行药物流产后清宫,观察胚胎排出情况及时间、腹痛情况。结果:停经10～14周服用药物流产后,胚胎完整排出率为64.7%,部分排出率为20.30%,失败率3.24%;完全流产者胚胎排出时间为服药后(5.20±2.58)h,不完全流产者胚胎排出时间为服药后(12.11±4.27)h。所有观察对象平均出血持续时间(8.38±2.65)d;完全流产者72 h阴道出血量(52.94±11.03)ml;不完全流产者72 h阴道出血量(66.32±16.15)ml;流产失败者72 h阴道出血量(26.94±6.25)mL。结论:米非司酮配伍米索前列醇用于终止10～14周妊娠具有效果好,成功率高等优点;在严密、谨慎应用的情况下,其安全、方便、损伤小,患者易于接受。
Objective:To investigate the mifepristone and misoprostol for 10 to 14 weeks of pregnancy,the clinical effect of Methods abdominal pain,menopause,10 to 14 weeks to terminate the pregnancy and medication contraindications for pregnant women using oral mifepristone and vaginal fornix misoprostol for medical abortion after Qing observed embryonic discharge and time,.Results menopause,10 to 14 weeks for the medication after medication abortion,embryonic complete discharge rate of 64.7%,part of the discharge rate of 20.30% failure rate of 3.24%;complete abortion embryos discharge time(5 20±2 and 58) h,incomplete abortion embryonic discharge time for the medication(12±4 11 27) h,.All observed objects mean bleeding duration(8 38±2 65) d;complete abortion,incomplete abortion by vaginal bleeding at 72 h 72 h,the amount of vaginal bleeding(52 of 94±03) ml.;(66 32±16 15) ml;abortion losers 72 h,vaginal bleeding(26 94±25) ml.Conclusion Mifepristone and Misoprostol for the termination of 10 to 14 weeks of gestation with good effect,and a high success rate;tight,cautious application of the case,the safe,convenient,injury,patients are easy to accept.
出处
《湖南师范大学学报（医学版）》
2012年第3期75-77,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
米非司酮
米索前列醇
妊娠
终止妊娠
mifepristone
misoprostol
pregnancy
termination of pregnancy
