摘要
目的研究首发老年抑郁症患者应用艾司西酞普兰与帕罗西汀治疗的临床效果与安全性。方法将2015年12月-2016年12月作为研究时段,选择此时间段内本院收治的96例首发老年抑郁症患者作为研究对象,随机将其分为对照组、观察组均为48例,给予对照组帕罗西汀治疗,观察组给予艾司西酞普兰治疗,比较分析两组患者的抑郁症状评分、临床治疗有效率、不良反应发生率。结果观察组抑郁症状评分、不良反应发生率明显低于对照组,且临床治疗有效率明显高于对照组(P<0.05)。结论在首发老年抑郁症患者的临床治疗中,应用艾司西酞普兰治疗,能有效改善抑郁症状,提高临床治疗效果,同时还可减少不良反应发生率,值得临床推广使用。
Objective To study the clinical effect and safety of the application of alzheimer's disease in patients with first-rate depression. Methods From December 2015 to December 2016 as the study period, 96 patients with senile depression were randomly divided into control group and the observation group, there were 48 cases in each group. The control group was treated with paroxetine, and the observation group was treated with escitalopram. The scores of depressive symptoms, clinical treatment and the incidence of adverse reactions were analyzed. Results The scores of depressive symptoms, the incidence of adverse reactions in the observation group was significantly lower than the control group, and the clinical treatment efficient was significantly higher than the control group(P 〈 0.05). ConclusionThe clinical treatment of patients with senile depression in the starting, the application of escitalopram citalopram treatment, can effectively improve depressive symptoms, improve the effect of clinical treatment, but also can reduce the incidence of adverse reactions, worthy of clinical promotion use.
出处
《中国卫生标准管理》
2017年第14期82-83,共2页
China Health Standard Management