摘要
目的 评价双黄烧伤软膏对烧伤常见感染性真菌的体外抑菌活性.方法 将临床分离的白色念珠菌、热带念珠菌、光滑念珠菌、近平滑念珠菌、烟曲霉菌、黑曲霉菌、黄曲霉菌、根霉菌制作含菌琼脂平板,应用改良琼脂扩散方法加入双黄烧伤软膏、克霉唑及酮康唑进行培养,观察菌株生长状况并测定抑菌圈直径.结果 双黄烧伤软膏在根霉菌培养基中形成明显抑菌圈,与克霉唑及酮康唑比较,差异有统计学意义（P〈0.05）.在各型曲霉菌及念珠菌培养基实验中,双黄烧伤软膏未形成明显抑菌环.结论 在体外实验中,双黄烧伤软膏对根霉菌具有一定抑制作用,对念珠菌及曲霉菌无明显作用.
Objective To evaluate the antibacterial activity of fungal infection about Shuanghuang burn ointment in vitro.Methods The clinical isolates of candida albicans,candida tropicalis,candida albicans,candida albicans,aspergillus fumigatus,aspergillus niger,aspergillus flavus and rhizopus were produced with agar plates containing bacteria.Application of modified agar diffusion method with Shuanghuang burn ointment and clotrimazole and ketoconazole were cultured.The growth status of the strain was observed and the diameter of bacteriostatic circle was determined.Results Shuanghuang burn ointment form obvious bacteriostatic ring in the culture medium of Rhizopus.Compared with clotrimazole and ketoconazole,there was significant difference（P〈0.05）.In the experiments of aspergillus and candida culturesm,Shuanghuang burn ointment could not form obvious bacteriostatic ring.Conclusion Shuanghuang burn ointment has certain inhibitory effect on rhizopus in vitro.There is no obvious effect on candida and aspergillus.
出处
《中国临床实用医学》
2017年第3期90-93,共4页
China Clinical Practical Medicine
基金
辽宁省自然基金项目（优秀人才培育）（2014020126）
关键词
真菌
烧伤
中药
双黄烧伤软膏
Fungi
Burns
Traditional Chinese medicine
Shuanghuang burn ointment
