摘要
腰椎间盘突出症(lambar disc herniation,LDH)是临床多发病、常见病。严重者可引起神经根或马尾神经功能障碍,非手术治疗很难治愈,复发率较高,而各种开放性手术对脊柱正常结构都会造成破坏,影响远期疗效。基于LDH导致临床症状出现的病因,利用经皮激光汽化减压术(percutaneous laser disc decompression,PLDD)的光热效应进行治疗取得良好的临床疗效,现将PLDD光热效应与LDH机械压迫与炎性细胞因子相互作用机理研究进行综述,以期更深入地了解PLDD的作用机制。
Lumbar disc herniation （LDH） is a common disease and may cause nerve root or cauda equina nerve dysfunction when it is seri- ous. It is hard to be cured with non-surgical treatment, the recurrence rate is high, and a variety of open surgeries on normal structures of spines will cause damages and affect the long-term effect of the treatment. Targeting at the clinical symptoms of LDH, the use of per- cutaneous laser vaporization decompression （percutaneous laser disc decompression, PLDD） has achieved good clinical efficacy with the photothermal effect of PLDD. For a better understanding of the mechanism of action of PLDD, the photothermal effect of PLDD and the interaction between LDH mechanical compression and inflammatory cell factors was reviewed in this article.
作者
赵继荣
王兴盛
王国慧
赵宁
ZHAO Ji-rong WANG Xing-sheng WANG Guo-hui ZHAO Ning(Gansu Provincial Hospital of TCM, Lanzhou 730050, China Gansu university of TCM Gansu University of Chinese Medicine)
出处
《中国激光医学杂志》
CAS
2017年第3期164-168,共5页
Chinese Journal of Laser Medicine & Surgery
基金
甘肃省自然科学基金项目(1606RJZA346)
