摘要
目的:通过Cyber Knife系统六维颅骨追踪(6D-skull)技术,研究分析发泡剂泡沫垫在头颈部肿瘤患者立体定向放射治疗中体位固定的优势。方法:选取30例接受立体定向放射治疗头部肿瘤患者,按照放射治疗中体位固定方式的不同将其分为观察组和对照组,每组15例。观察组为头颈肩低温热塑膜联合发泡剂固定,对照组为单纯头颈肩低温热塑膜固定。采用6D-skull技术获取患者治疗中体位误差值,比较两组患者分次治疗执行前体位误差、治疗中50 s采样点体位误差及体位位移量,并计算计划靶区(PTV)在X轴、Y轴和Z轴3个线性方向的外扩边界。结果:两组分次治疗执行前体位误差相比,无统计学差异(t=0.292,t=1.544,t=0.880,t=1.178,t=0.163,t=0.852;P>0.05);治疗中50 s采样点体位误差与体位位移量在3个线性方向有统计学差异(F=8.183,F=21.250,F=3.152,F=27.604,F=39.093,F=4.278;P<0.05),且观察组体位误差与体位位移量均小于对照组;两组3个旋转方向中L-R旋转和CW-CCW旋转体位误差比较有统计学差异(F=8.737,F=37.024;P<0.05),UP-DOWN旋转体位位移量比较有统计学差异(F=12.679;P<0.05)。两组分次治疗执行前与治疗中50 s采样点体位误差在Y轴线性方向PTV外扩范围差别较大,观察组PTV外扩0.421 mm和0.8424 mm;对照组PTV外扩1.162 mm和1.278 mm。X轴与Z轴线性方向PTV外扩范围差别较小。计算观察组PTV外扩范围均<1 mm。结论:发泡剂联合头颈肩低温热塑膜固定方法可以进一步提高头颈部肿瘤患者放射治疗体位固定的精确性,提升患者治疗中的舒适度,具有一定的临床应用价值。
Objective： To research and analyze the advantages of pad of styrofoam for patient with neck tumor in stereotactic radiotherapy through 6D-skull tracking technology of Cyberknife system. Methods： 30 patients with neck tumor who received stereotactic radiotherapy were divided into observation group that adopted combination mode of low temperature thermoplastic film and styrofoam for immobilization（15 cases） and control group that only adopted low temperature thermoplastic film（15 cases）. The error values about position of patients were obtained by using 6D-skull technique. The error values of body position before every treatment, the error values of body position at the sampling site of every 50 s during treatment and the displacement of body position between the two groups were compared. At the same time, extended boundaries of three linear directions（X-axis, Y-axis and Z-axis） of planning target volume（PTV） were calculated. Results： There were no significant differences between two groups before every treatment（t=0.292, t=1.544, t=0.880, t=1.178, t=0.163, t=0.852; P〈0.05）. At the three linear directions, the error values of body position among the sampling site of every 50 s between the two groups were statistically significant and the displacement of body position among them between the two groups also were statistically significant（F=8.183, F=21.250, F=3.152. F=27.604, F=39.093, F=4.278, P〈0.05）, and the observation group always smaller than control group in these comparisons. In three direction of rotation, the error values of body position in L-R rotation and CW-CCW rotation between the two groups were significant（F=8.737, F=37.024; P〈0.05）. And the displacement of body position in UP-DOWM rotation between two groups was significant（F=12.679; P〈0.05）. There were a great difference on the PTV extended range of the error value of body position on Y-axis linear direction before the every treatment and sampling site of every 50 s during treatment between the two group
出处
《中国医学装备》
2017年第7期32-36,共5页
China Medical Equipment
基金
国家重点研发计划(2016YFC0904600)"以生物组学特征与多模态功能影像为基础的多线束精准放疗方案研究"
关键词
头部肿瘤
定位发泡垫
摆位误差
立体定向放射治疗
六维颅骨追踪
Head tumor
Styrofoam of positioning
Positioning error
Stereotactic radiotherapy
Six dimensional-skull tracking
