摘要
The genus Artemisia is one of the largest and most widely distributed genera of the family Compositae. One type of the mainly active metabolites found in the Artemisia plants is sesquiterpenoids with extensive biological activities, including anti-inflammatory, immunomodulatory, anti-tumour, antimalarial, antinociceptive, antimierobial and other activities. In this review, we comprehensively summarized the progress concerning the phytochemistry and biological activities of sesquiterpenoids obtained from the Artemisia species from 2010 to July 2016. Furthermore, several future research perspectives and development of sesquiterpenoids as potential therapeutic agents were discussed as well.
蒿属为菊科中种类最多、分布最广的一个属。倍半萜类成分是该属植物中主要的活性成分之一,具有抗炎、免疫调节、抗肿瘤、抗疟、镇痛、抗菌等广泛的生物活性。本文对2010至2016年7月从蒿属植物中分离得到的倍半萜类成分的结构及生物活性进行了综述,同时对其开发利用的潜在前景进行了展望。
基金
National Natural Science Foundation of China(Grant No.31400305 and 81202916)
the Science and Technology Project of Henan Province(Grant No.152102310113)
the Science and Technology Project of the Education Department of Henan Province(Grant No.14A360012)
the Project for Youth Backbone Teachers in the University of Henan Province(Grant No.2015GGJS-130)
