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益母草注射液联合缩宫素对剖宫产产后出血的预防效果研究 被引量:27

Yimucao Injection combined with oxytocin in preventing postpartum hemorrhage after cesarean section
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摘要 目的研究益母草注射液联合缩宫素对剖宫产产后出血的预防效果。方法选择2015年1月—2016年6月乐山市妇幼保健院采取剖宫产分娩的产妇500例,随机分为两组,对照组仅单纯给予缩宫素,观察组联合给予缩宫素和益母草注射液。观察两组临床疗效、围手术期指标、术前和术后24 h血红蛋白、红细胞,记录两组不良反应的发生情况。结果观察组的总有效率为90.40%(226/250),明显高于对照组的73.20%(183/250),差异有统计学意义(P<0.05)。与对照组相比,观察组的术中出血量、术后2 h及24 h出血量明显减少,差异有统计学意义(P<0.05)。观察组的产后出血持续时间为(38.35±5.42)h,住院时间为(6.25±2.38)d,均明显短于对照组,差异有统计学意义(P<0.05)。观察组术后24 h血红蛋白、红细胞下降程度均明显低于对照组,差异有统计学意义(P<0.05)。结论益母草注射液联合缩宫素可有效预防剖宫产产后出血,减少术后出血量并缩短止血时间,安全有效。 Objective To investigate the clinical effect of Yimucao Injection combined with oxytocin in preventing postpartum hemorrhage after cesarean section.Methods 500 cases of pregnant women with cesarean section who were treated in Leshan Maternal and Child Health Hospital from January 2011 to June 2016 were divided into two groups randomly.The patients in the control group were only given oxytocin,while the patients in the observation group were given Yimucao Injection combined with oxytocin.To observe the clinical effect of the two groups,the amount of intraoperative hemorrhage volume,postoperative 2h bleeding,postoperative 24 h bleeding volume,the duration time of postpartum hemorrhage and hospitalization time,and the occurrence of adverse reactions in the two groups.Results The total effective rate of observation group was 90.40% (226/250),which was significantly higher than the control group 73.20 (183/250) (P 〈 0.05).Compared with the control group,the amounts of blood loss,2 h postoperative bleeding volume and 24 h postoperative bleeding volum in observation group were significantly decreased (P 〈 0.05).The duration time of postpartum hemorrhage and hospitalization time in observation group were significantly shorter than the control group (P 〈 0.05).24 h hemoglobin and red blood cell of the observation group were significantly lower than that of the control group (P 〈 0.05).The incidence of adverse reactions was significantly lower than that of the control group (P 〈 0.05).Conclusion Yimucao Injection combined with oxytocin can effectively reduce the amount of bleeding,shorten the time of bleeding and hospitalization time,safe and effective,which is worthy of clinical application.
作者 彭丽钦 李立
出处 《药物评价研究》 CAS 2017年第6期820-823,共4页 Drug Evaluation Research
关键词 剖宫产 产后出血 益母草注射液 缩宫素 cesarean section postpartum hemorrhage Yimucao Injection oxytocin
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