摘要
目的：探究卒中后抑郁合并心血管疾病患者通过早期综合干预后取得的临床成效。方法，选取我院2015年1月至2016年6月入院的卒中后抑郁合并心血管疾病患者80例，采用数字表法随机分为观察组和对照组，每一组40人。对照组治疗方法为常规基础治疗，对观察蛆在常规基础治疗基础上，口服百优解20mg／d，配合心理治疗。干预时间为4周。针对负性情绪、神经功能缺损及生存质量状况，对两组患者进行对比分析。结果：干预结束后，在负性情绪方面，观察组干预后焦虑和抑郁情绪改善情况明显优于对照组（P〈0.05）；针对神经功能缺损状况，观察组评分明显低于（P〈0．05）；在生存质量方面，观察组患者各项指标得分状况比对照组高（P〈0．05）。结论：卒中后抑郁合并心血管疾病患者通过早期综合干预可显著改善患者的神经功能，提高患者的生存质量，减轻患者焦虑、抑郁情绪，有一定的应用价值。
Objective ：To explore the clinical effect of early comprehensive therapy for post stroke depression. Methods： 80 cases of post stroke depression patients were selected from the patients who were admitted from January ,2015 to June ,2016. They were randomly divided into study group and control group. Each group has 40 cases. The treatment for the control group are regular treatments, while the treatment for the study group is comprehensive therapy .which include regular treatment, taking fluoxetine 20mg/day and psychological therapy .the time for intervention was 4 weeks. The negative emotions, neurology deficits and life quality were compared between the two groups .Results ：As far as negative emotions is concerned, the improvement for negative emotions in the study group is much better than those in the control group （P〈0.05）; the score of neurology deficits in the study group is lower than those in the control group （P〈0.05）. As far as life quality is concerned ,all index in the study group is higher than those in the control group （P〈0.05）. Conclusions： early comprehensive therapy can not only improve neurology function significantly, but also lessen the depressive symptoms ,anziety symptoms as well as improving life quality. It has potential clinical value for post stroke depression.
出处
《国际心血管病杂志》
2017年第A01期18-18,共1页
International Journal of Cardiovascular Disease
基金
广鹾医药卫生科研课题（Z2010119）
