摘要
目的探讨颅脑术后颅内感染的相关危险因素,为临床预防术后颅内感染提供参考。方法对2011年10月至2015年10月行开颅手术的1 049例的临床资料进行回顾性分析,根据纳入及排除标准排除68例,最终纳入981例。采用多因素Logistic回归分析检验危险因素。结果 981例中,术后发生颅内感染感染41例(4.2%)。多因素Logistic回归分析显示手术持续时间>4 h、颅后窝手术、脑室外引流术、置入性材料、发生脑脊液漏、糖尿病是颅脑术后发生颅内感染的独立危险因素(P<0.05)。结论严密缝合硬脑膜、缩短手术时间及脑室外引流时间、避免不必要的置入性材料、有效控制糖尿病病人血糖可有效预防、减少颅脑术后颅内感染。
Objective To explore the risk factors related to intracranial infection after craniotomy. Methods The clinical data of 1 049 patients undergoing craniotomy from October, 2011 to October, 2015, of whom, 981 were included in this study and 68 were excluded from this study according to the inclusion criteria and exclusion criteria, were analyzed retrospectively. Of those 981 patients, 41 （4.2%） had intracranial infection and 940 not according to the diagnostic criteria of the US Centers for Disease Control and Prevention. The risk factors related to intracranial infection were analyzed by statistics. Results The monofactorial analysis and multivariate logistic regression analysis showed that the risk factors related the intracranial infection after the craniotomy included the operative duration 〉4 hours, posterior cranial fossa surgery, external ventricular drainage （EVD）, implanted material, cerebrospinal fluid leakage and diabetes mellitus. Conclusion Strict aseptic technique, use of effective antibiotics during perioperative period, strict suturing of dura mater, shortening operative and EVD time, avoiding unnecessary implantation of materials, and effectively control of blood glucose in the diabetic patients can effectively reduce intracranial infection after the craniotomy.
出处
《中国临床神经外科杂志》
2017年第6期407-409,共3页
Chinese Journal of Clinical Neurosurgery
关键词
颅脑手术
颅内感染
危险因素
Craniotomy
lntracranial infection
Risk factors
Statistic analysis
