摘要
虽然晚期初治乳腺癌一直被认为是不可治愈的,但是合理的综合治疗已使部分患者看到了治愈的希望。作者综合大宗回顾性研究和ASCO会议三项前瞻性临床研究的结论,认为在保证全程有序、有效、可持续的系统性全身治疗前提下,年龄<55岁、激素受体阳性、肿瘤负荷轻、局部症状或体征明显的患者可以考虑原发肿瘤手术。对于该类患者是选择先接受原发肿瘤手术还是全身治疗仍然存在争议,而通过合理有效的综合治疗一定可以使患者的预后得到进一步改善。
Although de novo advanced breast cancer has long been considered incurable, reasonable comprehensive therapies could led some patients to be cured finally. According to the results of large retrospec- tive studies and three prospective clinical trials presented in American Society of Clinical Oncology （ASCO） conference, on the premise of ensuring of full-ordered course, effective and sustainable systemic treatment, pa- tients with aged 〈 55, hormone receptor positive tumors, light tumor burden, or obvious symptoms or signs of local lesions could be considered to accept the primary tumor resection. For those patients who should accept the primary tumor resection or systemic treatment at first is still controversial, however, reasonable and effective comprehensive therapies should be helpful to improve the prognosis of patients.
作者
雷蕾
王娴
王晓稼
LEI Lei WANG Xian WANG Xiaojia(Department of Breast Tumor Medical Oncology, Zhejiang Cancer Hospital, Hangzhou 310022, China Department of Medical Oncology, Sir Run Run Shaw Hospital affiliated to Zhejiang University School of Medicine ttangzhou 310016, China)
出处
《中国肿瘤外科杂志》
CAS
2017年第3期141-144,共4页
Chinese Journal of Surgical Oncology
基金
国家自然科学基金(No.81572715)
浙江省医药卫生科技计划(No.2015KYB052)
关键词
乳腺肿瘤
晚期乳腺癌
原发肿瘤手术
预后
Breast Ncoplasms
Advanced breast cancer
Primary lesion resection
Prognosis
