摘要
目的 分析腹型肥胖患者不同中医体质的临床特点。方法 选择2016年3—10月于北京中医药大学东直门医院住院的男性腹型肥胖患者60例。根据中医体质分型评估，将患者分为痰湿组和非痰湿组，各30例。收集并比较2组患者一般情况、血清生化指标及胰岛素抵抗指标。采用彩色超声诊断仪检测颈总动脉内中膜厚度（IMT）及动脉斑块回声、数量。结果 痰湿组空腹胰岛素、三酰甘油、胰岛素抵抗指数、颈总动脉IMT水平高于非痰湿组［（10.7±0.5）μg/L比（10.0±0.4）μg/L、（3.4±0.4）mmol/L比（2.7±0.5）mmol/L、（1.63±0.11）比（1.37±0.98）、（1.09±0.12）mm比（0.94±0.10）mm］，差异均有统计学意义（均P＜0.05）。痰湿组斑块低回声发生率高于非痰湿组［68.8%（11/16）比18.2%（2/11）］，差异有统计学意义（P＜0.05）。结论 痰湿质腹型肥胖患者颈总动脉IMT高于非痰湿质腹型肥胖患者，对2型糖尿病、心脑血管疾病具有更高的易感性。
Objective To analyze clinical characteristics of abdominal obese patients with different types of traditional Chinese medicine（TCM） constitution. Methods Sixty male patients with abdominal obesity from March 2016 to October 2016 in Dongzhimen Hospital, Beijing University of Chinese Medicine were enrolled. According to the type of TCM constitution, the patients were divided into phlegm-dampness group and non-phlegm-dampness group, with 30 cases in each group. Serum biochemical and insulin resistance indexes were tested. The common carotid intima-media thickness（IMT）, echo and number of arterial plaques were detected by color Doppler ultrasound. Results Levels of fasting insulin, triacylglycerol, insulin resistance index and carotid IMT in phlegm-dampness group were significantly higher than those in non-phlegm-dampness group[（10.7±0.5）μg/L vs （10.0±0.4）μg/L, （3.4±0.4）mmol/L vs （2.7±0.5）mmol/L, （1.63±0.11） vs （1.37±0.98）, （1.09±0.12）mm vs （0.94±0.10）mm]（P〈0.05）. The low echo rate in phlegm-dampness group was significantly higher than that in non-phlegm-dampness group[68.8%（11/16） vs 18.2%（2/11）]（P〈0.05）. Conclusion Patients with phlegm-dampness abdominal obesity have higher common carotid IMT and higher susceptibility to type 2 diabetes and cardiovascular diseases compared to non-phlegm-dampness abdominal obese patients.
作者
王琳
贺海东
王湘竹
康杰
董超
韦娜
于海容
张梅
Wang Lin He Haidong Wang Xiangzhu Kang Jie Dong Chao Wei Na Yu Hairong Zhang Mei(Department of Ultrasonography, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China Department of Clinical Laboratory, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, Chin)
出处
《中国医药》
2017年第7期1087-1089,共3页
China Medicine
基金
北京中医药大学基本科研业务费项目（2016-JYB-JSPY-028）
关键词
腹部肥胖症
痰湿质
胰岛素抵抗
颈总动脉内中膜
Obesity, abdominal
Phlegm-dampness
Insulin resistance
Carotid intima-media
